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CC BY-NC-ND 4.0 · World J Nucl Med 2021; 20(03): 312-315
DOI: 10.4103/wjnm.WJNM_79_20
Case Report

Follicular thyroid carcinoma metastasizing to rare sites and exhibiting variable inter-lesional heterogeneity on 18F-fluorodeoxyglucose positron emission tomography/computed tomography and 131I

Rahul V. Parghane
1   Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, Mumbai, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, Maharashtra, India
,
Sandip Basu
1   Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, Mumbai, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, Maharashtra, India
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Abstract

A patient of differentiated follicular thyroid carcinoma with unusual sites of metastases is illustrated with 131I and 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging findings. The described case harbored extremely rare metastasis to the urinary bladder with multi-organ metastatic disease (including unusual sites of right bronchus and hepatic metastases). There was inter-lesional heterogeneity among the metastatic lesions with regard to the 131I and FDG uptake in the aforementioned lesions. The detection of such heterogeneity has important implications for patient management in metastatic differentiated thyroid carcinoma.

Keywords

131I theranostics - 18F-fluorodeoxyglucose positron emission tomography/computed tomography - differentiated thyroid carcinoma - follicular thyroid carcinoma - urinary bladder metastasis

Financial support and sponsorship

Nil.




Publikationsverlauf

Eingereicht: 25. Juni 2020

Angenommen: 18. Juli 2020

Artikel online veröffentlicht:
24. März 2022

© 2021. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Kaplan AS, van Heerden JA, McMahon MM, Carpenter HA, Gharib H. Follicular carcinoma of the thyroid presenting with hematuria: A case report. Surgery 1986;100:572-5.
  • 2 Pepe P, Fraggetta F, Galia A, Grasso G, Aragona F. Hematuria as the presenting symptom of a metastatic thyroid cancer. Urol Int 2006;76:89-90.
  • 3 Grivas N, Housianitis Z, Doukas M, Stavropoulos NE. Follicular thyroid cancer metastasis to the urinary bladder: Report of a case and review of the literature. Case Rep Urol 2012;2012:178915.
  • 4 Ando T, Matsuo Y, Ikeoka T, Oba K, Miyata Y, Sakai H, et al. Gross hematuria and bladder tumor in a patient with advanced thyroid papillary carcinoma. Case Rep Endocrinol 2013;2013:585781.
  • 5 Nanni C, Rubello D, Fanti S, Farsad M, Ambrosini V, Rampin L, et al. Role of 18F-FDG-PET and PET/CT imaging in thyroid cancer. Biomed Pharmacother 2006;60:409-13.
  • 6 Basu S, Parghane RV. Grouping of metastatic thyroid carcinoma by molecular imaging features to allow for individualized treatment, with emphasis on the TENIS syndrome. J Nucl Med Technol 2016;44:184-9.
  • 7 Farina E, Monari F, Tallini G, Repaci A, Mazzarotto R, Giunchi F, et al. Unusual thyroid carcinoma metastases: A case series and literature review. Endocr Pathol 2016;27:55-64.
  • 8 Schlumberger M, Challeton C, De Vathaire F, Travagli JP, Gardet P, Lumbroso JD, et al. Radioactive iodine treatment and external radiotherapy for lung and bone metastases from thyroid carcinoma. J Nucl Med 1996;37:598-605.
  • 9 Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The American Thyroid Association Guidelines Task Force on thyroid nodules and differentiated thyroid cancer. Thyroid 2016;26:1-33.
  • 10 Lee JW, Lee SM, Lee DH, Kim YJ. Clinical utility of 18F-FDG PET/CT concurrent with 131I therapy in intermediate-to-high-risk patients with differentiated thyroid cancer: Dual-centre experience with 286 patients. J Nucl Med 2013;54:1230-6.
  • 11 Rosenbaum-Krumme SJ, Görges R, Bockisch A, Binse I. 18F-FDG PET/CT changes therapy management in high-risk DTC after first radioiodine therapy. Eur J Nucl Med Mol Imaging 2012;39:1373-80.