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CC BY-NC-ND 4.0 · World J Nucl Med 2021; 20(04): 336-341
DOI: 10.4103/wjnm.WJNM_112_20
Original Article

Comparison of gastric motility in patients of type 2 diabetes mellitus with various degrees of glycemic control

Sanchay Jain
Department of Nuclear Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
,
Vandana Dhingra
Department of Nuclear Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
,
Ravi Kant
1   Department of General Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
,
Ranjeeta Kumari
2   Department of Community and Family Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
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Abstract

The aim of this study was to evaluate the effect of glycemic control as estimated by glycated hemoglobin A1c (HbA1c) on gastric emptying in patients with type 2 diabetes mellitus (DM) using gastric emptying scintigraphy (GES). This was a cross-sectional study conducted at a tertiary health care center in Northern India. The study included 44 patients who underwent GES using a radiolabeled solid Idli meal containing 1 mCi of Tc-99 m Sulfur Colloid. Patients were divided into three groups based on glycemic control as Group A, B, and C with HbA1c <7%, 7%–9%, and >9%. Statistical analysis was performed using the IBM® SPSS® Statistics Version 23.0 The comparison of proportions was done using the Chi-square test and Fisher's exact test. Means were compared using the independent t-test and one-way analysis of variance. P < 0.05 was considered statistically significant. No statistically significant correlation was found between delayed gastric emptying and glycemic control (P = 0.09), gender (P = 0.228), dietary patterns (P = 0.91), symptoms of gastroparesis (P = 0.06), body mass index (BMI) (P = 0.267), and duration of type 2 DM (P = 0.565). No statistically significant association was also found between glycemic control and time taken for half gastric emptying (t1/2) (P = 0.225). Scintigraphy using Tc-99m Sulfur Colloid radiolabeled Idli meal can be effectively used for the assessment of gastric emptying. There is no significant correlation of delayed gastric emptying with glycemic control, gender, BMI, type of diet, and duration of diabetes mellitus.

Keywords

Diabetic gastroparesis - gastric emptying scintigraphy - hemoglobin A1c

Financial support and sponsorship

Nil.




Publication History

Received: 06 September 2021

Accepted: 19 September 2020

Article published online:
24 March 2022

© 2021. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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