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CC BY-NC-ND 4.0 · South Asian J Cancer 2019; 08(03): 166-167
DOI: 10.4103/sajc.sajc_182_18
ORIGINAL ARTICLE: GI Cancers

Calculation of a clinical predictive factors identifying peritoneal disease on a staging laparoscopy in gastric cancers

Caleb Harris
Department of Surgical Oncology, North Eastern Indira Gandhi Regional Institutes of Health and Medical Sciences, Shillong, Meghalaya
,
Vikas Ostwal
Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra
,
Dilip Harindran Vallathol
Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra
,
Rohit Dusane
Department of Clinical Research Secretariat, Tata Memorial Hospital, Mumbai, Maharashtra
,
Sarika Mandavkar
Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra
,
Shraddha Patkar
Department of Clinical Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra
,
Anant Ramaswamy
Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra
,
Shailesh V. Shrikhande
Department of Clinical Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Introduction: Staging laparoscopy (SL) is the current standard staging workup for loco-advanced gastric cancers (GCs). Materials and Methods: We analyzed the data of all patients with loco-regionally advanced, nonmetastatic GCs, who underwent SL for the evaluation of peritoneal carcinomatosis (PC). Results: Between December 2013 and October 2016, 363 patients underwent SL, of which 75 (20.7%) were found to have PC on SL. Age ≤40 years, CA 19-9 > upper limit of normal, and low serum albumin levels (≤3.5 g/dl) correlated significantly with the presence of PC on SL. There was a statistically significant difference in the median overall survival between patients with radiologically detected PC and SL detected PC (8.67 months vs. 15.3 months;P < 0.0001). Conclusion: SL upstaged disease status in 20.7% of patients. Clinical factors, identified in this study, need further validation in larger prospective cohorts before being used in clinical practice. Patients with radiologically detected PC have lower survival as compared to those with PC on SL.

Key words

Cervical canceComputed tomography scan - gastric cancers - peritoneal disease - predictive factors - staging laparoscopy

Supplementary Material



Publication History

Article published online:
21 December 2020

© 2019. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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