CC BY-NC-ND 4.0 · J Neuroanaesth Crit Care 2017; 04(04): S81-S84
DOI: 10.4103/jnacc-jnacc-1.17
Conference Proceeding
Thieme Medical and Scientific Publishers Private Ltd.

Desflurane in neurosurgery: Pros

Smita Sharma
1   Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra
,
Kiran Jangra
1   Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India
› Author Affiliations
Further Information

Publication History

Publication Date:
08 May 2018 (online)

Abstract

Neurosurgery and neuroanaesthesia are making rapid progress, and with this progress, there is the search for excellence and ideal results. The practice of neuroanaesthesia is fairly standardised today, and any debate can only be on the fine-tuning aspects of the techniques. The aim of all research in anaesthesia is to provide the best possible and safest operating conditions and to have a complete recovery at the end of the surgery. The maintenance of anaesthesia for neurosurgery is with balanced general anaesthesia which combines intravenous and inhalational agents. A review of literature shows that desflurane has definite advantages, and hence, it is an integral part of modern neuroanaesthesia.

 
  • REFERENCES

  • 1 Prabhakar H, Singh GP, Mahajan C, Kapoor I, Kalaivani M, Anand V. Intravenous versus inhalational techniques for rapid emergence from anaesthesia in patients undergoing brain tumour surgery. Cochrane Database Syst Rev 2016; 9: CD010467
  • 2 De Baerdemaeker LE, Struys MM, Jacobs S, Den Blauwen NM, Bossuyt GR, Pattyn P. et al. Optimization of desflurane administration in morbidly obese patients: A comparison with sevoflurane using an ‘inhalation bolus’ technique. Br J Anaesth 2003; 91: 638-50
  • 3 Caverni V, Rosa G, Pinto G, Tordiglione P, Favaro R. Hypotensive anesthesia and recovery of cognitive function in long-term craniofacial surgery. J Craniofac Surg 2005; 16: 531-6
  • 4 Bilotta F, Doronzio A, Cuzzone V, Caramia R, Rosa G. PINOCCHIO Study Group. Early postoperative cognitive recovery and gas exchange patterns after balanced anesthesia with sevoflurane or desflurane in overweight and obese patients undergoing craniotomy: A prospective randomized trial. J Neurosurg Anesthesiol 2009; 21: 207-13
  • 5 Bruder N, Pellissier D, Grillot P, Gouin F. Cerebral hyperemia during recovery from general anesthesia in neurosurgical patients. Anesth Analg 2002; 94: 650-4
  • 6 La Colla L, Albertin A, La Colla G, Mangano A. Faster wash-out and recovery for desflurane vs. sevoflurane in morbidly obese patients when no premedication is used. Br J Anaesth 2007; 99: 353-8
  • 7 Heavner JE, Kaye AD, Lin BK, King T. Recovery of elderly patients from two or more hours of desflurane or sevoflurane anaesthesia. Br J Anaesth 2003; 91: 502-6
  • 8 Sutton TS, Koblin DD, Gruenke LD, Weiskopf RB, Rampil IJ, Waskell L. et al. Fluoride metabolites after prolonged exposure of volunteers and patients to desflurane. Anesth Analg 1991; 73: 180-5
  • 9 Wulf H, Ledowski T, Linstedt U, Proppe D, Sitzlack D. Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflurane anaesthesia. Can J Anaesth 1998; 45: 526-32
  • 10 Chong CT, Manninen P, Sivanaser V, Subramanyam R, Lu N, Venkatraghavan L. Direct comparison of the effect of desflurane and sevoflurane on intraoperative motor-evoked potentials monitoring. J Neurosurg Anesthesiol 2014; 26: 306-12
  • 11 Sakabe T, Matsumoto M. Effects of anesthetic agents and other drugs on cerebral blood flow, metabolism, and intracranial pressure. In: Cottrell JE, Young WL. editors. Neuroanesthesia. 5th ed.. Philadelphia: Mosby Elsevier; 2010. p. 83
  • 12 Magni G, Rosa IL, Melillo G, Savio A, Rosa G. A comparison between sevoflurane and desflurane anesthesia in patients undergoing craniotomy for supratentorial intracranial surgery. Anesth Analg 2009; 109: 567-71
  • 13 Dube SK, Pandia MP, Chaturvedi A, Bithal P, Dash HH. Comparison of intraoperative brain condition, hemodynamics and postoperative recovery between desflurane and sevoflurane in patients undergoing supratentorial craniotomy. Saudi J Anaesth 2015; 9: 167-73
  • 14 Bastola P, Bhagat H, Wig J. Comparative evaluation of propofol, sevoflurane and desflurane for neuroanaesthesia: A prospective randomised study in patients undergoing elective supratentorial craniotomy. Indian J Anaesth 2015; 59: 287-94
  • 15 Bhat M, Bhagat H, Bhukal I. et al. Prospective randomized evaluation of propofol and desflurane in patients undergoing surgery for cerebellopontine angle. Available from: http://www.apicareonline.com
  • 16 Yasny JS, White J. Environmental implications of anesthetic gases. Anesth Prog 2012; 59: 154-8