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CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2021; 04(01): 19-22
DOI: 10.4103/jdep.jdep_5_20
Original Article

Accuracy of fine-needle aspiration cytology for detecting cancer in resected thyroid nodules at a referral hospital

Reem Alawadhi
Department of General Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates
,
Ahmad Matalkah
1   Department of General Surgery, Cleveland Clinic Abu Dhabi, Digestive Disease Institute, Abu Dhabi, United Arab Emirates
,
Naveed Ahmed
1   Department of General Surgery, Cleveland Clinic Abu Dhabi, Digestive Disease Institute, Abu Dhabi, United Arab Emirates
,
Ahmad Alduaij
2   Department of Anatomic Pathology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates
,
Alain Sabri
3   Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Lebanese American University, Byblos, Lebanon
,
Samer El-Kaissi
4   Department of Endocrinology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates
,
Yasir Akmal
1   Department of General Surgery, Cleveland Clinic Abu Dhabi, Digestive Disease Institute, Abu Dhabi, United Arab Emirates
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Background: Thyroid nodules are a common presentation in clinical practice. Fine-needle aspiration cytology (FNAC) is a useful method of triaging patients between benign, suspicious, and malignant categories. Materials and Methods: This is a retrospective review of the electronic medical record of all surgical thyroid patients presenting to our institution between July 2015 and June 2017. The cytological and histological data were reviewed and correlated based on the Bethesda system for reporting thyroid cytopathology. Results: Two hundred and seven patients underwent thyroidectomies during that period of which 164 had preoperative FNAC. The female-male ratio of 4.9:1. On histology, 52% of nodules were benign and 48% of nodules were malignant. When comparing with cytologic diagnosis, FNAC showed a sensitivity of 52%, specificity of 95%, positive predictive value of 92%, negative predictive value of 64%, false positive rate 5%, and false negative rate 48%. Total accuracy was found to be 72%. Conclusion: FNAC is a useful tool in deciding management options for patients, but has limitations, particularly when evaluating follicular lesions. This leads to discrepancy in the calculation of statistical values in literature.

Keywords

Fine needle-aspiration - middle east - thyroid cancer - thyroid nodules - thyroidectomy

Financial support and sponsorship

Nil.




Publikationsverlauf

Eingereicht: 05. Mai 2020

Angenommen: 24. Mai 2020

Artikel online veröffentlicht:
06. Juli 2022

© 2021. Gulf Association of Endocrinology and Diabetes (GAED). All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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