The American Diabetes Association (ADA) annual conference is the most notable annual
event in diabetes. Like many conferences in 2020 and 2021, it was held virtually due
to the COVID-19 pandemic. In this highlights summary, we selected the sections that
we felt are particularly relevant to practicing clinicians. The results of several
long-awaited studies were released. These include the GRADE study, SURPASS, and STEP
studies. The first ADA-European Association for the Study of Diabetes consensus on
the management of type 1 diabetes was also aired during the conference. Besides, the
AMPLITUDE-O study with new data on the cardiovascular and renal effects of Efpeglenatide
was published. The role of Teplizumab for the prevention of type 1 diabetes and Volagidemab
in patients with type 1 diabetes were discussed. Furthermore, the PROMISE study on
the safety and accuracy of next-generation 180 days implantable continuous glucose
monitoring systems was published. New news included advancing the role of glucagon
in treating and preventing severe hypoglycemia. Furthermore, the Effects on heart
failure with preserved ejection fraction from a pooled analysis of SOLOIST and SCORED
studies were presented. Finally, data on Dapagliflozin in COVID-19 (DARE-19) and the
STRENGTH versus REDUCE-IT studies were compared and contrasted. We hope to present
a concise summary of the conference highlights for those who missed the live event.
Keywords
American Diabetes Association - diabetes - education - glucagon - research - trials