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CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2020; 03(02): 63-69
DOI: 10.4103/jdep.jdep_10_19
Original Article

Effect of Fasting Therapy and Low-Calorie Diet on Anthropometric and Serum Lipids in Obese Females

Thittamarnahalli Honnegowda
0   Centre of Excellence, Government of India, SDM College of Naturopathy and Yogic Sciences, Dakshina Kannada, Karnataka, India
,
Prashant Shetty
1   Department of Natural Therapeutics, SDM College of Naturopathy and Yogic Sciences, Dakshina Kannada, Karnataka, India
,
H Shashikiran
2   Department of Naturopathy and Nutrition, SDM College of Naturopathy and Yogic Sciences, Dakshina Kannada, Karnataka, India
,
N Nandeesh
3   Department of Yoga, SDM College of Naturopathy and Yogic Sciences, Dakshina Kannada, Karnataka, India
,
P Arun
3   Department of Yoga, SDM College of Naturopathy and Yogic Sciences, Dakshina Kannada, Karnataka, India
,
Joysna Thayyil
4   Department of Microbiology, SDM College of Naturopathy and Yogic Sciences, Dakshina Kannada, Karnataka, India
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Background: Preclinical and clinical studies have shown the importance of calorie restriction diet in weight reduction and cardiovascular risk factors. In this study, our objective is to compare the naturopathic-based short-term fasting therapy with low-calorie diet (LCD) on anthropometric and lipid profile among obese and overweight persons. A total number of subjects (n = 100) with body mass index (BMI) ≥25 were randomly allocated into either fasting therapy intervention (n = 48) or a LCD (n = 52). Materials and Methods: Participants underwent very LCD (288–904 kcal) in fasting therapy and a LCD (1234 kcal) in the other group respectively for 10 days. Individuals in both the groups were assessed with anthropometric parameters such as BMI, weight, waist circumference, hip circumference and waist-hip ratio, serum lipid profile, and serum leptin levels at the baseline and after 10 days. Results: The anthropometric measurements were decreased significantly in the fasting group when compared with the LCD group (P < 0.05). The decrease in mean serum total cholesterol (TC) (−27.43%), triglycerides (TGs) (−13.05%), and low-density lipoprotein (LDL) (−20.9%) in the treated group were statistically significant (P < 0.001), whereas serum high density lipoprotein (2.32%) was increased but insignificantly (P > 0.001) when compared with the nontreated group. Conclusions: Our findings support that short-term fasting therapy is beneficial in anthropometric measures and reducing leptin level among obese or overweight person compared to LCD. However, long-term adherence of weight loss with these interventions should be tested in future studies with bigger sample size.

Keywords

Fasting therapy - low calorie diet anthropometry - low-calorie diet - naturopathy - serum lipid level

Financial support and sponsorship

Funding from the Ministry of AYUSH through Central Council for Research in Yoga and Naturopathy (CCRYN), Government of India, as part of a grant (Z 28015/74/2013-HPC (EMR) – AYUSH-B).




Publication History

Received: 22 June 2019

Accepted: 07 December 2019

Article published online:
16 June 2022

© 2020. Gulf Association of Endocrinology and Diabetes (GAED). All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 World Health Organization. Obesity and Overweight. World Health Organization; June, 2016. Available from: http://www.int/media centre/factsheets/fs311/en/. [Last accessed on 2017 Apr 10].
  • 2 Pradeepa R, Anjana RM, Joshi SR, Bhansali A, Deepa M, Joshi PP, et al. Prevalence of generalized and abdominal obesity in urban and rural India-the ICMR-INDIAB Study (Phase-I) [ICMR-NDIAB-3]. Indian J Med Res 2015;142:139-50.
  • 3 Kumar V, Cotran R, Robbins S. Basic Pathology 8th ed. Jakarta: EGC; 2007.
  • 4 Seabra A, Mendonça D, Maia J, Welk G, Brustad R, Fonseca AM, et al. Gender, weight status and socioeconomic differences in psychosocial correlates of physical activity in schoolchildren. J Sci Med Sport 2013;16:320-6.
  • 5 Szczygielska A, Widomska S, Jaraszkiewicz M, Knera P, Muc K. Blood lipids profile in obese or overweight patients. Ann Univ Mariae Curie Sklodowska Med 2003;58:343-9.
  • 6 Rucker D, Padwal R, Li SK, Curioni C, Lau DC. Long term pharmacotherapy for obesity and overweight: Updated meta-analysis. BMJ 2007;335:1194-9.
  • 7 Wolfe SM. When EMA and FDA decisions conflict: differences in patients or in regulation? BMJ 2013;347:f5140.
  • 8 Wood S. Diet Drug Orlistat Linked to Kidney, Pancreas Injuries. Medscape Medscape News Retrieved; 2011. p. 26.
  • 9 Gala DR. Efficacy of Fasting. Mumbai: Navneet Publications; 2000.
  • 10 Herbert Shelton M. The Science and fine Art of Fasting. 5th Revised edition. Chicago: Natural Hygiene; 1978.
  • 11 Lindlahr H. Nature Cure: Philosophy and Practice Based on the Unity of Disease and Cure. Chicago: The Nature Cure Publishing Company; 1922.
  • 12 Rao V. Panchatantra. 5th ed. India: Prakruthi Prakshya; 1979.
  • 13 Tsai AG, Wadden TA. The evolution of very-low-calorie diets: An update and meta-analysis. Obesity (Silver Spring) 2006;14:1283-93.
  • 14 Montesi L, El Ghoch M, Brodosi L, Calugi S, Marchesini G, Dalle Grave R. Long-term weight loss maintenance for obesity: A multidisciplinary approach. Diabetes Metab Syndr Obes 2016;9:37-46.
  • 15 Chan JL, Williams CJ, Raciti P, Blakeman J, Kelesidis T, Kelesidis I, et al. Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states. J Clin Endocrinol Metab 2008;93:2819-27.
  • 16 Ganesan K, Habboush Y, Sultan S. Intermittent Fasting: The Choice for a Healthier Lifestyle. Cureus 2018;10:e2947.
  • 17 Maurer S. Weight management in primary care. Visc Med 2016;32:342-6.
  • 18 Beer AM, Ismar LE, Wessely DK, Pötschke T, Weidner B, Wiebelitz KR. Retrospective long-term comparison of naturopathic fasting therapy and weight reduction diet in overweight patients. Evid Based Complement Alternat Med 2014;2014:453407. doi:10.1155/2014/453407.
  • 19 Kim KW, Song MY, Chung SH, Chung WS. Effect of modified fasting therapy on body weight, fat and muscle mass, and blood chemistry in patients with obesity. J Tradit Chin Med 2016;36:57-62.
  • 20 Frost G, Masters K, King C, Kelly M, Hasan U, Heavens P, et al. A new method of energy prescription to improve weight loss. J Hum Nutr Diet 2007;20:152-6.
  • 21 Johnston BC, Kanters S, Bandayrel K, Wu P, Naji F, Siemieniuk RA, et al. Comparison of weight loss among named diet programs in overweight and obese adults: A meta-analysis. JAMA 2014;312:923-33.
  • 22 Shetty P, Mooventhan A, Nagendra HR. Does short-term lemon honey juice fasting have effect on lipid profile and body composition in healthy individuals? J Ayurveda Integr Med 2016;7:11-3.
  • 23 Haluzík M, Matoulek M, Svacina S, Hilgertová J, Haas T. The influence of short-term fasting on serum leptin levels, and selected hormonal and metabolic parameters in morbidly obese and lean females. Endocr Res 2001;27:251-60.
  • 24 Johnston CS, Corte C, Swan PD. Marginal Vitamin C status is associated with reduced fat oxidation during submaximal exercise in young adults. Nutr Metab (Lond) 2006;3:35.
  • 25 Hu FB. Obesity Epidemiology [English]. New York: Oxford University Press; 2008.
  • 26 Slavin J. Why whole grains are protective: Biological mechanisms. Proc Nutr Soc 2003;62:129-34.
  • 27 Issa CM. Vitamin D and Type 2 Diabetes Mellitus. Adv Exp Med Biol 2017;996:193-205.
  • 28 Ye EQ, Chacko SA, Chou EL, Kugizaki M, Liu S. Greater whole-grain intake is associated with lower risk of type 2 diabetes, cardiovascular disease, and weight gain. J Nutr 2012;142:1304-13.
  • 29 Finnell JS, Saul BC, Goldhamer AC, Myers TR. Is fasting safe? A chart review of adverse events during medically supervised, water-only fasting. BMC Complement Altern Med 2018;18:67.
  • 30 Browning JD, Baxter J, Satapati S, Burgess SC. The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men. J Lipid Res 2012;53:577-86.
  • 31 Delbridge E, Proietto J. State of the science: VLED (Very Low Energy Diet) for obesity. Asia Pac J Clin Nutr 2006;15 Suppl: 49-54.
  • 32 Fock KM, Khoo J. Diet and exercise in management of obesity and overweight. J Gastroenterol Hepatol 2013;28 Suppl 4:59-63.
  • 33 Kramer A, Gollhofer A, Armbrecht G, Felsenberg D, Gruber M. How to prevent the detrimental effects of two months of bed-rest mscle, bone and cardiovascular system: An RCT Sci Rep 2017;7;13177. doi: 10.1038/s41598-017-13659-8.
  • 34 Wadden TA, Foster GD, Sarwer DB, Anderson DA, Gladis M, Sanderson RS, et al. Dieting and the development of eating disorders in obese women: Results of a randomized controlled trial. Am J Clin Nutr 2004;80:560-8.