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CC BY-NC-ND 3.0 · Journal of Digestive Endoscopy 2017; 08(04): 193-195
DOI: 10.4103/jde.JDE_17_17
Case Report
Journal of Digestive Endoscopy

Case of Cytomegalovirus Colitis in a Patient with Type 2 Diabetes Mellitus

Ankur Gupta
Department of Gastroenterology, Max Hospital, Dehradun, Uttarakhand, India
,
Priyanka Jain
1   Department of Gastroenterology Pathology, Max Hospital, Dehradun, Uttarakhand, India
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
25. September 2019 (online)

   Lizenzen und Reprints

ABSTRACT

Cytomegalovirus (CMV) colitis usually affects immunocompromised hosts. We report a patient with type 2 diabetes mellitus who presented with massive lower gastrointestinal bleed due to CMV colitis, which proved to be fatal. Awareness about this life-threatening entity is important in patients who have impaired immune response.

KEYWORDS

Cytomegalovirus - gastrointestinal bleed - immunity
 

  • REFERENCES

  • 1 Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011; 11: 98-107
    CrossrefPubMedGoogle Scholar
  • 2 Zhang LJ, Hanff P, Rutherford C, Churchill WH, Crumpacker CS. Detection of human Cytomegalovirus DNA, RNA, and antibody in normal donor blood. J Infect Dis 1995; 171: 1002-6
    CrossrefPubMedGoogle Scholar
  • 3 Nakase H, Herfarth H. Cytomegalovirus colitis, Cytomegalovirus hepatitis and systemic Cytomegalovirus infection: Common features and differences. Inflamm Intest Dis 2016; 1: 15-23
    CrossrefPubMedGoogle Scholar
  • 4 Rafailidis PI, Mourtzoukou EG, Varbobitis IC, Falagas ME. Severe Cytomegalovirus infection in apparently immunocompetent patients: A systematic review.. Virol J 2008; 5: 47
    CrossrefPubMedGoogle Scholar
  • 5 Ng FH, Chau TN, Cheung TC, Kng C, Wong SY, Ng WF. et al. Cytomegalovirus colitis in individuals without apparent cause of immunodeficiency. Dig Dis Sci 1999; 44: 945-52
    CrossrefPubMedGoogle Scholar
  • 6 Galiatsatos P, Shrier I, Lamoureux E, Szilagyi A. Meta-analysis of outcome of Cytomegalovirus colitis in immunocompetent hosts. Dig Dis Sci 2005; 50: 609-16
    CrossrefPubMedGoogle Scholar
  • 7 Heininger A, Jahn G, Engel C, Notheisen T, Unertl K, Hamprecht K. Human Cytomegalovirus infections in non-immunosuppressed critically ill patients. Crit Care Med 2001; 29: 541-7
    CrossrefPubMedGoogle Scholar
  • 8 Nasa M, Sharma Z, Sud R, Lipi L. Cytomegalovirus infection of gastrointestinal tract. Community Acquir Infect 2016; 3: 4-9
    CrossrefGoogle Scholar
  • 9 Goodman AL, Murray CD, Watkins J, Griffiths PD, Webster DP. CMV in the gut: A critical review of CMV detection in the immunocompetent host with colitis. Eur J Clin Microbiol Infect Dis 2015; 34: 13-8
    CrossrefPubMedGoogle Scholar
  • 10 Kishore J, Ghoshal U, Ghoshal UC, Krishnani N, Kumar S, Singh M. et al. Infection with Cytomegalovirus in patients with inflammatory bowel disease: Prevalence, clinical significance and outcome. J Med Microbiol 2004; 53 (Pt 11): 1155-60
    CrossrefPubMedGoogle Scholar