¹⁸F-FDG PET/CT in cyst infection in autosomal dominant polycystic kidney disease

Abstract

Infection of a cyst within an autosomal dominant polycystic kidney disease (ADPKD) is a serious complication. Diagnosis with conventional imaging techniques such as ultrasonography, computed tomography (CT), and magnetic resonance imaging can be sometimes challenging. The definite diagnosis is analysis of the cyst fluid, but cyst punctures can cause bleeding, rupture, and contamination of adjacent cysts. Recently, FDG PET/CT has been reported as a sensitive tool for detection of cyst infection. We describe a case of 63-year-old woman with infected cysts in the left kidney, in whom accurate diagnosis was made on FDG PET/CT. FDG PET/CT is an important investigation in patients with fever of uncertain etiology, where renal cyst infection is a possible cause, but other etiologies also need to be ruled out.

Keywords

Autosomal dominant polycystic kidney disease - FDG PET/CT - renal cyst infection

Publikationsverlauf

Eingereicht: 05. April 2019

Angenommen: 15. November 2019

Artikel online veröffentlicht:
19. Juli 2021

• References

• 1 Pei Y, Hwang YH, Conklin J, Sundsbak JL, Heyer CM, Chan W. et al. Imaging-based diagnosis of autosomal dominant polycystic kidney disease. J Am Soc Nephrol 2015; 26: 746-53
• 2 Jouret F, Lhommel R, Beguin C, Devuyst O, Pirson Y, Hassoun Z. et al. Positron-emission computed tomography in cyst infection diagnosis in patients with autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol 2011; 6: 1644-50
• 3 Gibson P, Watson ML. Cyst infection in polycystic kidney disease: A clinical challenge. Nephrol Dial Transplant 1998; 13: 2455-7
• 4 Sallée M, Rafat C, Zahar JR, Paulmier B, Grünfeld JP, Knebelmann B. et al. Cyst infections in patients with autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol 2009; 4: 1183-9
• 5 Sainaresh V, Jain Shh, Patel H, Shah P, Vanikar A, Trivedi H. Post transplant urinary tract infection in autosomal dominant polycystic kidney disease a perpetual diagnostic dilema-18-fluorodeoxyglucose- positron emission computerized tomography—A valuable tool. Indian J Nucl Med 2011; 26: 109-11
• 6 Agrawal K, Bhattacharya A, Singh SK, Manohar K, Kashyap R, Mittal BR. Polycystic kidney disease: Renal cyst infection detected on F-18 FDG PET/CT. Clin Nucl Med 2011; 36: 1122-3
• 7 Piccoli GB, Arena V, Consiglio V, Deagostini MC, Pelosi E, Douroukas A. et al. Positron emission tomography in the diagnostic pathway for intracystic infection in ADPKD and “cystic” kidneys: A case series. BMC Nephrol 2011; 12: 48
• 8 Oyama N, Ito H, Takahara N, Miwa Y, Akino H, Kudo T. et al. Diagnosis of complex renal cystic masses and solid renal lesions using PET imaging: Comparison of11 C-acetate and18 F-FDG PET imaging. Clin Nucl Med 2014; 39: e208-14
• 9 Paschali AN, Georgakopoulos AT, Pianou NK, Anagnostopoulos CD. 18 F-Fluorodeoxyglucose positron emission tomography/computed tomography in infected polycystic kidney disease. World J Nucl Med 2015; 14: 57-9
• 10 Bobot M, Ghez C, Gondouin B, Sallée M, Fournier PE, Burtey S. et al. Diagnostic performance of [(18) F] fluorodeoxyglucose positron emission tomographycomputed tomography in cyst infection in patients with autosomal dominant polycystic kidney disease. Clin Microbiol Infect 2016; 22: 71-7
• 11 Albano D, Bosio G, Bertagna F. 18 F-FDG PET/CT demonstrated renal and hepatic cyst infection in a patient with autosomal dominant polycystic kidney disease. Nucl Med Rev 2016; 19: 26-8
• 12 Pij JP, Kwee TC, Slart RHJA, Glaudemans AWJM. FDG PET/CT for diagnosis of cyst infection in autosomal dominant polycystic kidney disease. Clin Transl Imaging 2018; 6: 61-7