Appraisal of radiation dose with 64-slice computed tomography perfusion in lung cancer patients with special reference to SSDE: An initial experience in a tertiary care hospital

Shuchi Bhatt; Ajai K Srivastava; Neha Meena; Shweta Thakur

doi:10.4103/ijri.IJRI_44_17

Indian Journal of Radiology and Imaging, Table of Contents

CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2017; 27(04): 389-396
DOI: 10.4103/ijri.IJRI_44_17

Thoracic/ Cardiac

Appraisal of radiation dose with 64-slice computed tomography perfusion in lung cancer patients with special reference to SSDE: An initial experience in a tertiary care hospital

Authors

Shuchi Bhatt

Department of Radio-diagnosis, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India
Ajai K Srivastava

Department of Radio-diagnosis, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India
Neha Meena

Department of Radio-diagnosis, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India
Shweta Thakur

Department of Radio-diagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Abstract

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Abstract

Context: Computed tomography perfusion (CTP) is an important functional tool for lung cancer. It is expected to deliver high radiation dose, making its accurate estimation important. Size-specific dose estimate (SSDE) is a new dose metric, which includes the scanner output as well as the patient size. Aims: To determine radiation dose [CT dose index (CTDI_vol), dose length product (DLP), effective dose (ED), and SSDE] for CTP in lung cancer and the correlation of CTDI_vol, DLP, and SSDE with effective diameter and SSDE with weight, body mass index (BMI), and the scan length. Settings and Design: Cross-sectional study in the Department of Radio-diagnosis from October 2015 to March 2016. Patients and Methods: Due ethical approval and informed consent was taken. Thirty consecutive adult patients of lung cancer undergoing CTP study were included; various radiation dose parameters were determined and presented as mean ± SD. Statistical Analysis Used: Paired Student's t-test and Pearson correlation using Statistical Package for the Social Sciences, Version 16. Results: Mean radiation dose was CTDI_vol = 270.138 ± 1.627 mGy, DLP = 681 ± 53.496 mGy.cm, ED = 12.501 ± 0.923 mSv, SSDE = 388.90 ± 81.27 mGy. The CTDI_vol and DLP had significant positive correlation (r = 0.556, P= 0.000 and r = 0.522, P= 0.003, respectively) with effective diameter. SSDE had strong negative correlation (r = −0.997, P= 0.000) with effective diameter, significant negative correlation with the BMI (r = −0.889; P= 0.000) and weight (r= −0.910, P= 0.000) of patients. Scan length was not significantly correlated in SSDE (r = −0.012, P= 0.951). Conclusions: Smaller sized patients had greater SSDE.

Keywords

Lung cancer - multidetector computed tomography - patient safety - perfusion imaging - radiometry

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