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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2018; 28(02): 161-164
DOI: 10.4103/ijri.IJRI_320_17
Neuroradiology & Head and Neck Imaging

First case of neurofibromatosis with posterior reversible encephalopathy syndrome showing spinal cord involvement

Pui Kwan Joyce Chan
Department of Radiology and Imaging, Queen Elizabeth Hospital, Kowloon, Hong Kong (SAR), People’s Republic of China
,
Kin Sun Tse
Department of Radiology and Imaging, Queen Elizabeth Hospital, Kowloon, Hong Kong (SAR), People’s Republic of China
,
Wing Shan Elaine Fok
Department of Radiology and Imaging, Queen Elizabeth Hospital, Kowloon, Hong Kong (SAR), People’s Republic of China
,
Wai Lun Poon
Department of Radiology and Imaging, Queen Elizabeth Hospital, Kowloon, Hong Kong (SAR), People’s Republic of China
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Subject Editor: Financial support and sponsorship Nil.
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Abstract

Posterior reversible encephalopathy syndrome (PRES) is a well-documented pathology of the brain in systemic upsets. Majority of PRES cases present with edema in the cerebrum, most commonly in the territory of posterior circulation. It has been reported to show spinal cord involvement in a rare subgroup known as PRES with spinal cord involvement (PRES-SCI), with very limited existing literature even in adult patients. Our institution recently encountered a pediatric case with neurofibromatosis type I (NF 1) showing PRES with extensive reversible spinal cord changes. This case illustrates the features of this rare entity in the pediatric group of patients, and is the first reported case in NF 1 patients.

Keywords

Hypertensive crisis - neurofibromatosis - pediatric posterior reversible encephalopathy syndrome - posterior reversible encephalopathy syndrome - spinal cord edema


Publication History

Article published online:
26 July 2021

© 2018. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Bartynski W, Boardman J. Distinct imaging patterns and lesion distribution in posterior reversible encephalopathy syndrome. Am J Neuroradiol 2007; 28: 1320-7
    CrossrefPubMedGoogle Scholar
  • 2 Neurofibromatosis. National Institutes of Health Consensus Statement. Online 1986; 6: 1-19
    Google Scholar
  • 3 Bartynski W. Posterior reversible encephalopathy syndrome, Part 1: Fundamental imaging and clinical features. Am J Neuroradiol 2008; 29: 1036-42
    CrossrefPubMedGoogle Scholar
  • 4 de Havenon A, Joos Z, Longenecker L, Shah L, Ansari S, Digre K. Posterior reversible encephalopathy syndrome with spinal cord involvement. Neurology 2014; 83: 2002-6
    CrossrefPubMedGoogle Scholar
  • 5 Nagato M, Takahashi Y, Yoshioka M, Nambu M. A case of hypertensive encephalopathy with extensive spinal lesions on MRI. Brain Dev 2010; 32: 598-601
    CrossrefPubMedGoogle Scholar
  • 6 Yiş U, Karaoğlu P, Kurul S, Soylu A, Çakmakçi H, Kavukçu S. Posterior reversible leukoencephalopathy syndrome with spinal cord involvement in a 9-year-old girl. Brain Dev 2016; 38: 154-7
    CrossrefPubMedGoogle Scholar
  • 7 Yasuda Y, Akiguchi I, Imai T, Sonobe M, Kage M. Hypertensive brainstem encephalopathy. Internal Med 2003; 42: 1131-4
    CrossrefPubMedGoogle Scholar
  • 8 DeBella K, Szudek J, Friedman J. Use of the National Institutes of Health Criteria for diagnosis of neurofibromatosis 1 in children. Pediatrics 2000; 105: 608-14
    CrossrefPubMedGoogle Scholar
  • 9 Friedman JM. Neurofibromatosis 1. 1998 [Updated Sep 4, 2014]. In: Pagon RA, Adam MP, Ardinger HH. et al. editors GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2017
    Google Scholar