CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2017; 27(02): 237-240
DOI: 10.4103/ijri.IJRI_238_16
Breast

Differentiation of secondary involvement of the breast by lymphoreticular malignancy from fibroadenoma using ultrasound elastography: A report of two cases

Eren Abdulkadir
Department of Radiology, School of Medicine, Medipol University, Istanbul, Turkey
,
Ertan Gulhan
Department of Radiology, School of Medicine, Medipol University, Istanbul, Turkey
,
Sila Ulus
Department of Radiology, School of Medicine, Acibadem University, Istanbul, Turkey
› Author Affiliations
Financial support and sponsorship Nil.

Abstract

Extramedullary lymphoma infiltration of the breast by lymphoblastic lymphoma is very rare and most cases are of B-cell lineage; T-cell neoplasms represent less than 10% of all breast lymphomas. Here, we report one patient with lymphoblastic lymphoma and one patient with leukemia, who have similar lesions in breasts with different ultrasound elastography findings. Ultrasound-guided tru-cut biopsies were performed and the first lesion was confirmed as lymphoma infiltration and the second as fibroadenoma. In cases of breast mass presence in patients with a history of hematologic malignancies such as lymphoma or leukemia, breast infiltration should be kept in mind. Elastography findings can assist in the differentiation of these lesions and further investigations or biopsies can be avoided.



Publication History

Article published online:
27 July 2021

© 2017. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 Karbasian-Esfahani M, Wiernik PH, Yeddu M, Abebe L. Leukemic infiltration of the breast in acute lymphocytic leukemia (ALL). Hematology 2008;13:101-6.
  • 2 Mandal S, Jain S, Khurana N. Breast lump as an initial manifestation in acute lymphoblastic leukemia: An unusual presentation. A case report. Hematology 2007;12:45-7.
  • 3 Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T, et al. Breast disease: Clinical application of US elastography for diagnosis. Radiology 2006;239:341-50.
  • 4 Memis A, Killi R, Orguc S, Ustun EE. Bilateral breast involvement in acute lymphoblastic leukemia: Color Doppler sonography findings. AJR Am J Roentgenol 1995;165:1011.
  • 5 Asai S, Miyachi H, Kubota M, Koyanagi N, Ogawa Y, Hotta T, et al. In: Ueno E, Shiina T, Kubota M, Sawai K, editors. Ultrasonographic appearance and clinical implication of bilateral breast infiltration with leukemia cells. Research and development in breast ultrasound. Tokyo: Springer; 2005. p. 185-9.
  • 6 Cunningham I. A clinical review of breast involvement in acute leukemia. Leuk Lymphoma 2006;47:2517-26.
  • 7 Surov A, Wienke A, Abbas J. Breast leukemia: An update. Acta Radiol 2012;53:261-6.
  • 8 Ebner L, Bonel HM, Huber A, Ross S, Christe A. Diagnostic Performance and Additional Value of Elastosonography in Focal Breast Lesions: Statistical Correlation between Size-Dependant Strain Index Measurements, Multimodality-BI-RADS Score, and Histopathology in a Clinical Routine Setting. ISRN Radiol 2014;2014:396368.
  • 9 Sadigh G, Carlos RC, Neal CH, Dwamena BA. Accuracy of quantitative ultrasound elastography for differentiation of malignant and benign breast abnormalities: A meta-analysis Breast Cancer Res Treat 2012;134:923-31.
  • 10 Pourbagher A. Breast Involvement in Acute Lymphoblastic Leukemia. Cukurova Med J 2015;40:64-70.