Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2018; 39(04): 546-547
DOI: 10.4103/ijmpo.ijmpo_97_17
Case Report

Stauffer’s Syndrome: A Rare Paraneoplastic Syndrome with Renal Cell Carcinoma

Mayank Jain
Departments of Gastroenterology, Gleneagles global Health City, Chennai, Tamil Nadu, India
,
Joy Varghese
Departments of Hepatology, Gleneagles global Health City, Chennai, Tamil Nadu, India
,
K M Muruganandham
Departments of Urology, Gleneagles global Health City, Chennai, Tamil Nadu, India
,
Jayanthi Venkataraman
Departments of Gastroenterology, Gleneagles global Health City, Chennai, Tamil Nadu, India
› Author Affiliations Financial support and sponsorship Nil.
› Further Information
   Permissions and Reprints

Abstract

An elderly male patient presented with cholestatic jaundice and weight loss. On evaluation, he was found to have left renal mass and hepatomegaly. Diagnosis of Stauffer’s syndrome was confirmed based on his clinical history, biochemical evaluation, and liver biopsy. Resolution of jaundice was noted after removal of the renal mass.

Keywords

Cholestasis - jaundice - paraneoplastic - renal


Publication History

Article published online:
17 June 2021

© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Sharara AI, Panella TJ, Fitz JG. Paraneoplastic hepatopathy associated with soft tissue sarcoma. Gastroenterology 1992; 103: 330-2
    CrossrefPubMedGoogle Scholar
  • 2 Karakolios A, Kasapis C, Kallinikidis T, Kalpidis P, Grigoriadis N. Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma. Clin Gastroenterol Hepatol 2003; 1: 480-3
    CrossrefPubMedGoogle Scholar
  • 3 Saintigny P, Spano JP, Tcherakian F, Pailler MC, Breau JL. Non-metastatic intrahepatic cholestasis associated with bronchial adenocarcinoma. Ann Med Interne (Paris) 2003; 154: 171-5
    Google Scholar
  • 4 Morla D, Alazemi S, Lichtstein D. Stauffer’s syndrome variant with cholestatic jaundice: A case report. J Gen Intern Med 2006; 21: C11-3
    CrossrefPubMedGoogle Scholar
  • 5 Dourakis SP, Sinani C, Deutsch M, Dimitriadou E, Hadziyannis SJ. Cholestatic jaundice as a paraneoplastic manifestation of renal cell carcinoma. Eur J Gastroenterol Hepatol 1997; 9: 311-4
    CrossrefPubMedGoogle Scholar
  • 6 Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E. et al. Cancer statistics, 2004. CA Cancer J Clin 2004; 54: 8-29
    CrossrefPubMedGoogle Scholar
  • 7 Gold PJ, Fefer A, Thompson JA. Paraneoplastic manifestations of renal cell carcinoma. Semin Urol Oncol 1996; 14: 216-22
    PubMedGoogle Scholar
  • 8 Stauffer MH. Nephrogenic hepatomegaly. Gastroenterology 1961; 40: 694
    Google Scholar
  • 9 Blay JY, Rossi JF, Wijdenes J, Menetrier-Caux C, Schemann S, Négrier S. et al. Role of interleukin-6 in the paraneoplastic inflammatory syndrome associated with renal-cell carcinoma. Int J Cancer 1997; 72: 424-30
    CrossrefPubMedGoogle Scholar