CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2018; 39(02): 125-126
DOI: 10.4103/ijmpo.ijmpo_92_17
Editorial Commentary

Adding Olanzapine to Three Drugs Anti Emetic Regimen: Is it Time to Jump the Gun?

Aditi Aggarwal
Department of Radiotherapy and Oncology, Maulana Azad Medical College, New Delhi, India
,
Vinod Sharma
Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India
,
Sameer Rastogi
Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India
› Author Affiliations
Financial support and sponsorship Nil.

Background

Field of cancer supportive care is rapidly evolving and number of anti-emetic agents has been approved and added to treatment arsenal in the past two decades. Not unexpectedly, in a worldwide online survey (ASCO 2014), antiemetics were voted among the “Top 5 advances in 50 years of modern oncology.”[1] Combination regimen are current standard of care, targeting the polypharmacology of chemotherapy-induced nasua and vomiting (CINV), especially in highly emetogenic chemotherapy regimen (HEC). However, polypharmacy has potential for additive side effects and may not be cost effective. Indeed, one has to focus on strategies, so to achieve the best with the least.



Publication History

Article published online:
23 June 2021

© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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