Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(03): 381-382
DOI: 10.4103/ijmpo.ijmpo_28_20
Trainee’s Corner

Next Generation Sequencing

Guruprasad Bhat
Department of Medical Oncology, Yenepoya Specialty Hospital, Mangalore, Karnataka, India
,
Amit Kumar Jain
Department of Medical Oncology, Artemis Hospital, Gurugram, Haryana, India
› Author Affiliations Financial support and sponsorship Nil.
› Further Information
   Permissions and Reprints

Next generation sequencing (NGS) has revolutionized the field of medicine and research and has improved on the principles of first-generation sequencing (Sanger Sequencing).



Publication History

Received: 27 January 2020

Accepted: 18 March 2020

Article published online:
28 June 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Sanger F, Coulson AR. A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. J Mol Biol 1975; 94: 441-8
    CrossrefPubMedGoogle Scholar
  • 2 Grada A, Weinbrecht K. Next-generation sequencing: Methodology and application. J Invest Dermatol 2013; 133: e11
    CrossrefPubMedGoogle Scholar
  • 3 Heather JM, Chain B. The sequence of sequencers: The history of sequencing DNA. Genomics 2016; 107: 1-8
    CrossrefPubMedGoogle Scholar
  • 4 Kamps R, Brandão RD, Bosch BJ, Paulussen AD, Xanthoulea S, Blok MJ. et al. Next-generation sequencing in oncology: Genetic diagnosis, risk prediction and cancer classification. Int J Mol Sci 2017; 18: 308
    CrossrefPubMedGoogle Scholar