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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2018; 39(01): 75-78
DOI: 10.4103/ijmpo.ijmpo_28_17
Review Article

Vitamin D Role in Prevention of Cancer: Overview

T G Shrihari
Department of Oral Medicine and Radiology, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India
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Abstract

Vitamin D is the name given to a group of fat-soluble prohormones. Two major forms of Vitamin D that are important to humans are Vitamin D2 or ergocalciferol and Vitamin D3 or cholecalciferol. Vitamin D2 is made naturally by the body when the skin is exposed to ultraviolet radiation (in particular, ultraviolet B [UVB] radiation) in sunlight. Vitamin D2 and Vitamin D3 can also be commercially manufactured. The active form of Vitamin D in the body is 1,25-dihydroxyvitamin D or calcitriol, which can be made from either Vitamin D2 or Vitamin D3. Evidence suggests that Vitamin D helps in the prevention of various cancers such as breast cancer, colorectal cancer, prostate cancer, head and neck cancer, and other cancers. This review article briefs about the role of Vitamin D in the prevention of cancer.

Keywords

Cancer - Vitamin D - Vitamin D3 (1 - 25-dihydroxycholecalciferol - calcitriol)


Publication History

Article published online:
23 June 2021

© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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