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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2019; 40(S 01): S176-S180
DOI: 10.4103/ijmpo.ijmpo_258_17
Practitioner Section

Langerhans Cell Histiocytosis in a 5-Year-Old Girl: A Case Report and Review of Literature

Shruthi Rao
Consultant, General Dental Practitioner, Mangala Health Centre, Padil, Karnataka, India
,
Shruthi Hegde
Departments of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Karnataka, India
,
PS Gopinath Thilak
Departments of Oral and Maxillofacial Surgery and Oral Pathology and Microbiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Karnataka, India
,
G Subhas Babu
Departments of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Karnataka, India
,
Vidya Ajila
Departments of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Karnataka, India
,
Urvashi Shetty
Departments of Oral Pathology and Microbiology, A B Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Karnataka, India
,
Sajad Ahmad Buch
Departments of Research Scholar, Yenepoya Dental College, Yenopoya (Deemed to be) University, Mangaluru, Karnataka, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Langerhans cell histiocytosis (LCH) is an uncommon hematological disorder affecting infants and young children. LCH is a rare disorder of the reticuloendothelial system associated with proliferation of Langerhans cells and mature eosinophils. LCH can involve any bone, but the most common are pelvis, ribs, skull, long bones, vertebra, and facial bones. In the skull, frontal and parietal bones are commonly involved followed by the jaws, where mandible is more commonly affected than the maxilla. In this article, we report a case of LCH in a 5-year-old child involving the mandible. Swelling of one side of the face and aggressive periosteal reaction led to the diagnosis of monostotic LCH. The manuscript also summarizes the results of a literature search in PubMed of reported cases of LCH over the past 10 years.

Keywords

Langerhans cell histiocytosis - mandible - periostitis


Publication History

Article published online:
24 May 2021

© 2019. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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