Abstract
Chronic myeloid leukemia (CML) is the most common leukemia presenting with priapism.
Due to social stigma or shyness, the real incidence of priapism in our population
is difficult to estimate. Since the successful development of tyrosine kinase inhibitors,
the life expectancy of CML-chronic phase (CML-CP) has been comparable to the healthy
population, and the importance of priapism has further magnified. As of now, the long-term
outcome and fertility issues are not very well known. We present the case of a 24-year-old
previously healthy gentleman who presented with priapism and was diagnosed as CML-CP.
He achieved major molecular response at 18 months. On follow-up at 2 years since the
diagnosis, he offers no complaint except moderate erectile dysfunction (International
Index of Erectile Function score 11), compromising his quality of life.
Keywords
Chronic myeloid leukemia - erectile dysfunction - imatinib - priapism