CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(03): 439-440
DOI: 10.4103/ijmpo.ijmpo_219_19
Letter to Editor

Myroides and Neurology: An Overview

Jamir Pitton Rissardo
Department of Medicine, Federal University of Santa Maria, Santa Maria, Rio Grand do Sul, Brazil
Ana Letícia Fornari Caprara
Department of Medicine, Federal University of Santa Maria, Santa Maria, Rio Grand do Sul, Brazil
› Author Affiliations
Financial support and sponsorship Nil.


We read the article, “Myroides odoratus central nervous infection in a postneurosurgery patient” on the esteemed “Indian Journal of Medical and Paediatric Oncology” with great interest. Bhat et al. reported a case of meningitis secondary to M. odoratus followed by supratentorial craniotomy due to a recurrent right frontal malignant brain tumor that arises from astrocytes.[1]

M. odoratus and Myroides odoratimimus are two important species of the Flavobacteriales order that cause infections in humans.[2] In this context, pericardial effusion, pericarditis, pneumonia, soft tissue infection, septic shock, and urinary tract infection were already associated with these microorganisms. However, neurological infections were rarely reported in literature.[3]

Here, we would like to provide a comparison between the two causes already published in the literature [Table 1].[1],[4] An interesting fact to be highlighted is that even though Myroides species infections are one of more resistant organisms in literature, in majority of the reports the individuals had full recovery.[3]

Table 1

Case reports of patients with neurological infections by Myroides species


Macfarlane et al

Bhat et al

API – Analytical profile index

Year, country

1985, Jamaica

2019, India


6 weeks/male

37 years/female



Anaplastic astrocytoma in the right frontal lobe

Central nervous system infection

Meningitis (hydrocephalus and ventriculitis)

Meningitis following supratentorial craniotomy

Microorganism identified

Not clearly specified. It is described as Flavobacterium odoratum

Myroides odoratus

Performing tests for organism identification

Standard biochemical tests and API 2oE

VITEK (BioMerieux, Marcyl’Etoile, France) automated identification system and desferrioxamine (250 pgdisc) susceptibility testing


First intravenous with penicillin and gentamicin. After no improvement, intraventricular cefotaxime was started

Vancomycin and cefoperazone-sulbactam. After susceptibility results, vancomycin was withdrawn


Full recovery

Full recovery of the infection

A recent article by Hu et al. revealed that the comparative analysis of some Myroides strains is phylogenetically related with similar genomes. Furthermore, their study showed that clustered regularly interspaced short palindromic repeats were found in two of the organisms. Thus, these results substantially contribute to a better understanding of the bacterial pathogenicity and antibiotic resistance mechanisms of this genus.[5]

Publication History

Received: 27 October 2019

Accepted: 06 January 2020

Article published online:
28 June 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

  • References

  • 1 Bhat VG, Vira HJ, Shetty P, Gupta S. Myroides odoratus central nervous infection in a postneurosurgery patient. Indian J Med Paediatr Oncol 2019; 40: 291-3
  • 2 Vancanneyt M, Segers P, Torck U, Hoste B, Bernardet JF, Vandamme P. et al. Reclassification of Flavobacterium odoratum (Stutzer 1929) strains to a new genus, Myroides, as Myroides odoratus comb. nov. and Myroides odoratimimus sp. nov.. Int J Syst Evol Microbiol 1996; 46: 926-32
  • 3 Benedetti P, Rassu M, Pavan G, Sefton A, Pellizzer G. Septic shock, pneumonia, and soft tissue infection due to Myroides odoratimimus: Report of a case and review of Myroides infections. Infection 2011; 39: 161-5
  • 4 Macfarlane DE, Baum-Thureen P, Crandon I. Flavobacterium odoratum ventriculitis treated with intraventricular cefotaxime. J Infect 1985; 11: 233-8
  • 5 Hu S, Cao L, Wu Y, Zhou Y, Jiang T, Wang L, Sarin YK. et al. Comparative genomic analysis of Myroides odoratimimus isolates. Microbiologyopen 2019; 8: e00634