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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(04): 456-460
DOI: 10.4103/ijmpo.ijmpo_169_16
Original Article

Squamous Cell Carcinoma Lung with Skeletal Muscle Involvement: A 8‑year Study of a Tertiary Care Hospital in Kashmir

Javvid Muzamil
Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India
,
Shumail Bashir
Department of Chest Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India
,
Faisal R Guru
Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India
,
Firdousa Nabi
Department of Prosthodonsia, Government Dental College, Srinagar, Jammu and Kashmir, India
,
Gull Mohammad Bhat
Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Aims: Lung cancer is the mostcommon malignancy throughout the world. Nonsmall cell lung cancer (NSCLC) is the mostcommon type, and squamous cell type is mostcommon in India. Mostly, patients present with chest-related symptoms and signs. Isolated skeletal muscle metastasis (ISMM) is rarely seen. The aim was to see muscle metastasis and its prognosis. Materials and Methods: We are presenting our data of 8 years about thiscommon malignancy with relation to muscle metastasis, either alone or with other system metastasis. Results: Muscle metastasis is seen 1.5% of patients, with male: female of 8:1. Overall median survival was 15 months and progression-free survival was 12 months. Conclusion: One peculiarity seen was ISMM with no pulmonary system and severe paraneoplastic hypercalcemia. Local therapy may be having an impact on overall survival in metachronous muscle involvement.

Keywords

Cytokeratin - isolated skeletal muscle metastasis - nonsmall cell lung carcinoma - overall survival - parathyroid hormone-related peptide - progression-free survival - superior vena cava - thyroid transcription factor


Publication History

Article published online:
04 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used forcommercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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