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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(05): 677-682
DOI: 10.4103/ijmpo.ijmpo_164_19
Original Article

Neoplasms of the Head and Neck in Iranian Children and Adolescents

Saede Atarbashi-Moghadam
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Mohammad Taghi Haghi Ashtiani
Department of Pathology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
,
Maryam Barati
Dental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Soran Sijanivandi
Dental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Introduction: Head and neck neoplasms afflict all age groups including children. They manifest with various histological features and clinical behaviors. This study's aim was to provide data and analysis of the prevalence of head and neck neoplasms among the Iranian children and adolescents to help pathologists and clinicians make informed diagnosis and treatment decisions. Materials and Methods: This retrospective study was based on medical records of children and adolescents (≤18 years) documented at a prestigious children's medical center stationed in Tehran, Iran. Cases diagnosed with head and neck tumors recorded from 2005 to 2016 were selected. Patients' age and sex, tumors' sites, and microscopic types were assessed. Data analysis was performed using descriptive statistics. Results: Of the 41,409 available pediatric patients' records documented over 12 years, 418 cases (1.01%) recorded head and neck tumors. Of these 418 cases, 15 recorded metastatic tumors (3.58%) and 403 recorded primary tumors. Of the primary tumors, 386 were found in the soft tissue (95.78%) and 17 in the bone (4.22%). The primary tumor patients' mean age was 5.46 years, including boys (59.8%) and girls (40.2%). The neck was the most common primary tumors' location (57.32%). Of all the primary tumors, 54.6% were benign neoplasms and 45.4% malignant. The commonest benign tumors were hemangioma/lymphangioma, and the most common malignancy was lymphoma. Mesenchymal neoplasms were the most common microscopic group followed by hematopoietic tumors. Conclusions: The analysis of these data indicates that the prevalence of pediatric head and neck tumors in the Iranian population is similar to other countries.

Keywords

Children - head and neck tumor - hemangioma - lymphoma - malignant


Publication History

Received: 01 August 2019

Accepted: 03 April 2020

Article published online:
17 May 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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