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DOI: 10.4103/ijmpo.ijmpo_145_20
Advanced Thyroid Cancer Controversy and Consensus
The overall incidence of differentiated thyroid cancers displaying aggressive behavior, by local invasion, distant metastasis, treatment resistance, and increased mortality ranges between 10% and 15%.[1],[2],[3],[4] Due to this relatively low incidence and unstandardized definition for locally advanced thyroid cancers (LATC), there is a great amount of discrepancy regarding the definition and management of LATC. There is also a lack of good quality prospective studies to guide the correct approach and management of this group of patients. Majority of existing papers have a distinct heterogeneity in the subject population and disease characteristics. All existing guidelines are derived from retrospective observational studies with possible bias and incomplete data.
In this review, we would like to highlight the main controversies and possible consensus in the management of LATCs.
Publication History
Received: 09 April 2020
Accepted: 11 June 2020
Article published online:
17 May 2021
© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
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