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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(04): 624
DOI: 10.4103/ijmpo.ijmpo_136_19
Letter to Editor

Concurrent Hairy Cell Leukemia and Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications

Parameswaran Anoop
Department of Hemato-Oncology, Apollo Hospitals, Bengaluru, Karnataka, India
,
Channappa N Patil
Department of Hemato-Oncology, Apollo Hospitals, Bengaluru, Karnataka, India
,
Venkatachalam Sandhya
Department of Pathology, Apollo Hospitals, Bengaluru, Karnataka, India
,
Sonal Dhande
Department of Hemato-Oncology, Apollo Hospitals, Bengaluru, Karnataka, India
,
Kalpana Janardan
Department of Internal Medicine, Apollo Hospitals, Bengaluru, Karnataka, India
,
Shivali Ahlawat
Department of Hematopathology, Oncquest Laboratories, New Delhi, India
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Sir,

Our patient who had concurrent chronic lymphocytic leukemia and hairy cell leukemia, viral serological markers including HIV and hepatitis viruses B and C were tested by the highly sensitive chemiluminescent immunoassay method. With this screening immunoassay, although false positivity can occur, the probability of false negativity is extremely low. This patient tested negative for all the three viruses. He was a previously fit and well gentleman and in light of the above negative tests, we did not think it prudent to further pursue CD4 counts and viral load estimation by polymerase chain reaction. These details could not be incorporated in the original case report due to word limit restrictions. However, the point raised of HIV predisposing to multiple lympho-proliferative malignancies is well taken.



Publication History

Received: 07 June 2019

Accepted: 19 September 2019

Article published online:
17 May 2021

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