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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(04): 555-558
DOI: 10.4103/ijmpo.ijmpo_130_16
Case Report

A Case of Multifocal Eosinophilic Granuloma Involving Spine and Pelvis in a Young Adult: A Radiopathological Correlation

Santosh Rai
Department of Radiodiagnosis, Kasturba Medical College (Manipal University), Mangalore, Karnataka, India
,
H B Sridevi
Department of Pathology, Kasturba Medical College (Manipal University), Mangalore, Karnataka, India
,
Radha R Pai
Department of Pathology, Kasturba Medical College (Manipal University), Mangalore, Karnataka, India
,
Pulastya Sanyal
Department of Radiodiagnosis, Kasturba Medical College (Manipal University), Mangalore, Karnataka, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

We present a case of multiple osteolytic lesions in a 28-year-old adult who presented with headache, back pain, and hip pain of 6 months. There was no history of localized swelling or rise of temperature, no history of weight loss or evening rise of temperature. On examination, there were no focal neurological deficits. Routine laboratory investigations, including total leukocyte counts, differential leukocyte counts, hemoglobin, and platelet counts, were within normal limits. There was a borderline elevation of erythrocyte sedimentation rate. Non enhancedcomputer tomography (NECT) demonstrated no abnormality in the brain or skull bones. However, incidentally, a lytic lesion involving the third cervical (C3) vertebral body and the neural arch was detected which also demonstrated a soft tissuecomponent adjacent to the lytic lesion. These findings warranted further work up; and magnetic resonance imaging of whole spine and pelvis was performed that revealed multiple bony lesions involving the cervical vertebrae, head and neck, bilateral femur, sacrum, and iliac bones. Computed tomography-guided biopsy was performed from the C3 vertebral lytic lesion which showed features of eosinophilic granuloma on histopathological evaluation.

Keywords

Eosinophilic granuloma - multiple lytic lesions - radiological


Publication History

Article published online:
04 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used forcommercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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