Subscribe to RSS
DOI: 10.4103/ijmpo.ijmpo_128_17
Adrenocortical Carcinoma: A Rare Tumor in a 12-year-old Girl
Financial support and sponsorship Nil.
Abstract
A 12-year-old girl presented with intra-abdominal mass and cushingoid features. On investigation, she was diagnosed as a case of functioning adrenocortical carcinoma. Two cycles of neoadjuvant chemotherapy followed by excision of mass with right nephrectomy was performed. On 6-month follow-up, recurrence and metastasis were identified which were managed with surgery and chemotherapy.
Publication History
Article published online:
17 June 2021
© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Stiller CA. International variations in the incidence of childhood carcinomas. Cancer Epidemiol Biomarkers Prev 1994; 3: 305-10
- 2 Allolio B, Fassnacht M. Clinical review: Adrenocortical carcinoma: Clinical update. J Clin Endocrinol Metab 2006; 91: 2027-37
- 3 Anonymous. General melasma and short hair over the entire body of a child of three years, with conversion of the left supra-renal capsule into a large malignant tumor; The external organs of generation resembling that of adult life. Lancet 1865; 1: 175
- 4 Michalkiewicz E, Sandrini R, Figueiredo B, Miranda EC, Caran E, Oliveira-Filho AG. et al. Clinical and outcome characteristics of children with adrenocortical tumors: A report from the international pediatric adrenocortical tumor registry. J Clin Oncol 2004; 22: 838-45
- 5 Ng L, Libertino JM. Adrenocortical carcinoma: Diagnosis, evaluation and treatment. J Urol 2003; 169: 5-11
- 6 Mendonca BB, Lucon AM, Menezes CA, Saldanha LB, Latronico AC, Zerbini C. et al. Clinical, hormonal and pathological findings in a comparative study of adrenocortical neoplasms in childhood and adulthood. J Urol 1995; 154: 2004-9
- 7 Veytsman I, Nieman L, Fojo T. Management of endocrine manifestations and the use of mitotane as a chemotherapeutic agent for adrenocortical carcinoma. J Clin Oncol 2009; 27: 4619-29
- 8 Berruti A, Fassnacht M, Baudin E, Hammer G, Haak H, Leboulleux S. et al. Adjuvant therapy in patients with adrenocortical carcinoma: A position of an international panel. J Clin Oncol 2010; 28: e401-2