Subscribe to RSS
Download PDF
DOI: 10.4103/ijmpo.ijmpo_114_18
Primary Neuroendocrine Carcinoma of Kidney: Report of a Rare Case
Financial support and sponsorship Nil.
Abstract
Primary neuroendocrine tumor (NET) of kidney is extremely rare, with <100 cases reported so far. The aim of the present case study is to discuss the clinical and pathological findings of renal NET and review of the available literature. We herein report the case of a 42-year-old female patient, who presented with pain abdomen and hematuria. Immunohistochemistry of her nephrectomy specimen was positive for chromogranin A and CD56 and negative for uroplakin II, P40, and CD10. KI index was 60%. Due to rarity of the tumor, there are no established guidelines available for its treatment. She was treated with combination chemotherapy of cisplatin and etoposide.
Publication History
Received: 14 May 2018
Accepted: 21 June 2018
Article published online:
23 May 2021
© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Litwinowicz R, Szpor J, Januś G, Worek M, Okoń K. Primary carcinoid tumour in horseshoe kidney. Pol J Pathol 2011; 62: 72-4
- 2 Murali R, Kneale K, Lalak N, Delprado W. Carcinoid tumors of the urinary tract and prostate. Arch Pathol Lab Med 2006; 130: 1693-706
- 3 Kawajiri H, Onoda N, Ohira M, Nakatani T, Wakasa K, Ishikawa T. et al. Carcinoid tumor of the kidney presenting as a large abdominal mass: Report of a case. Surg Today 2004; 34: 86-9
- 4 Fjällskog ML, Granberg DP, Welin SL, Eriksson C, Oberg KE, Janson ET. et al. Treatment with cisplatin and etoposide in patients with neuroendocrine tumors. Cancer 2001; 92: 1101-7
- 5 Romero FR, Rais-Bahrami S, Permpongkosol S, Fine SW, Kohanim S, Jarrett TW. et al. Primary carcinoid tumors of the kidney. J Urol 2006; 176: 2359-66
- 6 Hansel DE, Epstein JI, Berbescu E, Fine SW, Young RH, Cheville JC. Renal carcinoid tumor: A clinicopathologic study of 21 cases. Am J Surg Pathol 2007; 31: 1539-44
- 7 Lane BR, Jour G, Zhou M. Renal neuroendocrine tumors. Indian J Urol 2009; 25: 155-60
- 8 Lane BR, Chery F, Jour G, Sercia L, Magi-Galluzzi C, Novick AC. et al. Renal neuroendocrine tumours: A clinicopathological study. BJU Int 2007; 100: 1030-5
- 9 Korkmaz T, Seber S, Yavuzer D, Gumus M, Turhal NS. Primary renal carcinoid: Treatment and prognosis. Crit Rev Oncol Hematol 2013; 87: 256-64