The survival of Ewing's sarcoma (ES) has improved due to advances in both local and
systemic therapy. This has given rise to an increased detection of second malignant
neoplasms which can be in the form of solid tumors and hematological malignancies.
The most common hematological malignancies are acute myeloid leukemia/myelodysplastic
syndrome. Acute lymphoblastic leukemia (ALL) is relatively uncommon in occurrence
in this setting. Furthermore, the average refractory period for hematological malignancies
varies from 3 to 5 years. We report a case of a young female who developed ALL while
on adjuvant therapy for ES.
Keywords
Acute lymphoblastic leukemia - Ewing's sarcoma - secondary malignancy