Long-term hemodialysis (HD) is the main modality used in the treatment of end-stage
renal disease (ESRD). It is associated with a variety of complications such as infection,
amyloidosis, anemia, undernutrition, as well as musculoskeletal, and cardiovascular
system (CVS) morbidities. CVS complications and HD-related infection are the main
causes of death in ESRD patients on HD. Other complications such as stroke, disequilibrium
syndrome occur during or post-HD. Missing dialysis sessions may lead to amongst others;
death due to sudden cardiac arrhythmias; cardiac arrest due to electrolyte disturbance
and/or severe overload. This review discusses the common complications of HD as well
as recent advances that are likely to impact its outcome.
Key-words:
Amyloidosis - cardiovascular disease - end-stage renal disease - hemodialysis - infection
- long-term - renal osteodystrophy - undernutrition