CC BY-NC-ND 4.0 · Eur J Dent 2017; 11(02): 221-225
DOI: 10.4103/ejd.ejd_354_16
Original Article
Dental Investigation Society

Hypochlorite solution for root canal irrigation that lacks a chlorinated odor

La-ongthong Vajrabhaya
1   Endodontic Section, Faculty of Dental Medicine, Rangsit University, Pathum Thani, Thailand
,
Vanida Sangalungkarn
2   Department of Pharmacology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
,
Ratchapin Srisatjaluk
3   Department of Microbiology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
,
Suwanna Korsuwannawong
4   Research Office, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
,
Chareerut Phruksaniyom
2   Department of Pharmacology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
23. September 2019 (online)

ABSTRACT

Objectives: This is an in vitro study to develop a formulation of a hypochlorite solution for root canal irrigation that lacks a chlorinated odor. The antibacterial effect, tissue dissolution efficacy, and the cytotoxicity of the solution were assessed in cell culture and were compared with those of commercial sodium hypochlorite (NaOCl) solutions. Materials and Methods: Trichloroisocyanuric acid (TCA) was used as the source of hypochlorite ions in solution. All required properties of the NaOCl irrigant were evaluated and compared with those of original 2.5% NaOCl solutions currently in use. Results: Our results revealed that a TCA 3.5% + 1/6 Buffer-1 solution passed the short-term stability test. Moreover, no odor of chlorine gas was detected by three independent observers. The hypochlorite ion content and pH were stable over an incubation period of 4 weeks. The new solution did not differ from commercial products in terms of the dissolution property on bovine pulpal tissue (P > 0.05). Moreover, the antibacterial effect of this solution on Enterococcus faecalis did not differ from that of the commercial products (P > 0.05). In addition, our biocompatibility analysis demonstrated no difference among the tested solutions (P > 0.05). Conclusions: According to the results of all properties tested, TCA 3.5% + 1/6 Buffer-1 could be considered an option for NaOCl irrigation with the benefit of no detectable chlorine odor.

 
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