Subscribe to RSS

DOI: 10.4103/ajns.AJNS_521_20
A severe case of brain myiasis: Treatment rationale and review of literature

Cerebral myiasis is a rare condition caused by a parasitic infestation of fly larvae feeding on the host's necrotic or living tissue. Only 16 cases of cerebral myiasis have been published. We presented the case of a 72-year-old man with a neglected infestation of an extensive ulcerative cancer of the scalp. A large cranial lesion, with exposed brain and dura mater and severe Sarcophaga carnaria maggot infestation, was evident. We gently removed the maggots and covered the defect with thick gauze and sodium hypochlorite solution dressing. We additionally present a review of the literature to highlight shared features and suggestions for care management. In all cases, there was an absence of fatal meningitis and encephalitis, which is surprising given the open skull erosion with prolonged cortical exposure and points to the protective effects of larvae wound infestation.
Financial support and sponsorship
Nil.
Publication History
Received: 03 December 2020
Accepted: 26 March 2021
Article published online:
16 August 2022
© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Sesterhenn AM, Pfützner W, Braulke DM, Wiegand S, Werner JA, Taubert A. Cutaneous manifestation of myiasis in malignant wounds of the head and neck. Eur J Dermatol 2009;19:64-8.
- 2 Piña-Tornés AA, Salvador-Fernández CL, Lindao-Camacho R, González-Longoria-Boada LB, Vintimilla-Burgos NP, Selles Almarales M. Massive cutaneous myiasis mimicking brain invasion. Case report and literature review. MÉD.UIS. 2016;29:145-53.
- 3 Cheshier SH, Bababeygy SR, Higgins D, Parsonnet J, Huhn SL. Cerebral myiasis associated with angiosarcoma of the scalp: Case report. Neurosurgery 2007;61:E167.
- 4 Aggarwal A, Maskara P. Maggots in the brain: Sequelae of ignored scalp wound. World Neurosurg 2018;109:115-6.
- 5 Gabriel JG, Marinho SA, Verli FD, Krause RG, Yurgel LS, Cherubini K. Extensive myiasis infestation over a squamous cell carcinoma in the face. Case report. Med Oral Patol Oral Cir Bucal 2008;13:E9-11.
- 6 Zhou X, Kambalame DM, Zhou S, Guo X, Xia D, Yang Y, et al. Human Chrysomya bezziana myiasis: A systematic review. PLoS Negl Trop Dis 2019;13:e0007391.
- 7 Gilly R, Lapras C, Mamelle JC, Challamel MJ, Ghilhot JH, Nicolas A, et al. Hypodermic migrant myiasis with intracerebral hematoma. Apropos of a case in a 7-year-old child. Pediatrie 1976;31:67-75.
- 8 Navarro JN, Alves RV. Postoperative cerebral myiasis: A rare cause of wound dehiscence in developing countries. Surg Neurol Int 2016;7:69.
- 9 Giri SA, Kotecha N, Giri D, Diyora B, Nayak N, Sharma A. Cerebral myiasis associated with artificial cranioplasty flap: A case report. World Neurosurg 2016;87:661.e13-6.
- 10 Marco de Lucas E, Díez C, Gutiérrez A, Montiaga F, Arnáiz J, Mandly AG, et al. Unusual MRI findings in a patient with history of frontal fracture and skin infestation by fly larvae, as a possible sign of intracerebral myiasis. Clin Neurol Neurosurg 2008;110:725-8.
- 11 Zucoloto S, Rossi MA. Facial myiasis with spreading to the cranial vault. Rev Bras Med 1971;28:13-6.
- 12 Froomin LL. Intradural cyst of parasitic origin (myiasis clinic). Zh Ushn Nos Gorl Bolezn 1939;16:427-33.
- 13 Kalelioğlu M, Aktürk G, Aktürk F, Komsuoğlu SS, Kuzeyli K, Tiğin Y, et al. Intracerebral myiasis from Hypoderma bovis larva in a child. Case report. J Neurosurg 1989;71:929-31.
- 14 Terterov S, Taghva A, MacDougall M, Giannotta S. Posttraumatic human cerebral myiasis. World Neurosurg 2010;73:557-9.
- 15 Arbit E, Varon RE, Brem SS. Myiatic scalp and skull infection with diptera Sarcophaga: Case report. Neurosurgery 1986;18:361-2.
- 16 Rossi MA, Zucoloto S. Fatal cerebral myiasis caused by the tropical warble fly, Dermatobia hominis. Am J Trop Med Hyg 1973;22:267-9.
- 17 Pouillaude JM, Dupont J, Gilly R, Lapras C. Intracerebral myiasis in a child. Pediatr Radiol 1980;10:121-3.
- 18 Tauziede-Espariat A. Infections of the Central Nervous System: Pathology and Genetics, 2020. Chapter 49: Brain myiasis. doi: 10.1002/9781119467748.ch49]. [doi: 10.1002/9781119467748.ch49].
- 19 Semenov PV. A case of penetration of Hypoderma lineatum de Villers larva into the human brain. Med Parazitol (Mosk) 1969;38:612-3.