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CC BY-NC-ND 4.0 · Asian J Neurosurg 2021; 16(02): 402-405
DOI: 10.4103/ajns.AJNS_470_20
Case Report

Pathological diversity in schwannomas of the orofacial region

Aadithya Urs
Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi
,
Priya Kumar
Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi
,
Jeyaseelan Augustine
Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi
,
Rewa Malhotra
Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi
,
Kiran Jot
Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi
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Schwannoma is a slow-growing, encapsulated benign tumor of the neuroectodermal origin arising from the perineural Schwann cells. This study aims to elucidate the clinicoradiographical and histopathological features of orofacial schwannomas through a case series of seven cases. The patients' aged ranged from 13 to 45 years, with a male predilection in the ratio of 5:2. One intraosseous case presented as a radiolucent lesion. All the cases exhibited Antoni A and Antoni B type of microscopic patterns in varying amounts. One case of ancient schwannoma showed degenerative features. The tumor cells showed diffuse positive immunohistochemical reaction for S-100 protein. Our study suggests that intraosseous schwannoma should be considered in the differential diagnosis of the intraosseous jaw lesions. Histopathologically, it is important to recognize the findings of ancient schwannoma and to avoid misdiagnosing it as a malignant lesion.

Key-words:

Ancient schwannoma - Antoni A and Antoni B areas - intraosseous schwannoma - S-100 protein - Verocay bodies

Financial support and sponsorship

Nil.




Publication History

Received: 15 October 2020

Accepted: 15 February 2021

Article published online:
16 August 2022

© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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