Background: Anterior cervical discectomy with fusion (ACDF) is a proven method for the treatment
of selected patients. The necessity of use of an anterior plate is controversial.
The article aims to assess the fusion rates (FRs) and long-term outcomes following
three-level ACDF. Materials and Methods: Data were collected from the medical records of patients operated on due to degenerative
cervical disease. All patients were treated with three-level ACDF employing polyether
ether-ketone cages without anterior plating. Visual analog scale (VAS), neck disability
index (NDI), and plain radiographs were used in the clinical and radiological postsurgery
assessment. Fusion evaluation was performed according to the <1 mm motion between
spinous processes rule. Subsidence was defined as a more than 2 mm decrease in the
interbody height. Results: A total of 234 treated levels on 78 patients were assessed. The mean presurgery NDI
score was 23.07 ± 4.86, with a mean disability of 46.03% ± 9.64. The mean presurgery
VAS score of the neck was 7.58 ± 0.85, while VAS score of the arm was 7.75 ± 1.008.
Post surgery, NDI stated no disability, while VAS score of the neck and arm showed
no presence of pain. The mean FR was 19.50 ± 21.71 levels per month, with a peak from
3rd to 6th month. Presurgery evaluation showed 12 (15.38%) patients with a high T2 sequence
signal. Magnetic resonance imaging screening detected 31 (39.24%) patients with coexisting
cervical and lumbar findings. Post surgery, transient dysphagia was reported by 1
patient (1.28%), while subsidence was registered in 15 (6.41%) levels, situated in
12 patients (15.38%), most often at C6-7 (66.6%). Clinical and radiological follow-up extended to 69.47 ± 11.45 months. Conclusion: Multilevel stand-alone ACDF is a safe, cost-effective procedure providing favorable
clinical and radiological results with minimal complications. The incidence of subsidence
is usually clinically insignificant and can be decreased with a careful surgical technique.
Key-words:
Anterior cervical discectomy - fusion - outcome - stand alone