CC BY-NC-ND 4.0 · J Lab Physicians 2019; 11(04): 385-387
DOI: 10.4103/JLP.JLP_55_19
Case Report

Von Meyenburg complex clinically presenting as metastatic liver nodule: A rare finding in an elderly male

Nadia Shirazi
Department of Pathology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
,
Neena V Chauhan
Department of Pathology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
,
Smita Chandra
Department of Pathology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
,
Sunil Saini Kumar
Department of Surgery, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
› Author Affiliations
Financial support and sponsorship Nil.

Abstract

Von Meyenburg complex is a benign biliary hamartoma observed in approximately 3% of the autopsies conducted. These hamartomas are small, multiple and can be seen anywhere in the liver. There is usually no abnormality in liver function tests, and the patient is mostly asymptomatic. They serve as a diagnostic dilemma, particularly during metastatic workup in suspected cancer patients. Imaging studies are usually noncontributory, and biopsy is necessary for a definite diagnosis. We present here a middle-aged North Indian male who underwent liver biopsy to rule out metastasis.



Publication History

Received: 03 April 2019

Accepted: 01 November 2019

Article published online:
07 April 2020

© 2019.

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 von Meyenburg H. About the liver cyst. Beitr Pathol Anat 1918;64:477-535.
  • 2 Redston MS, Wanless IR. The hepatic von Meyenburg complex: Prevalence and association with hepatic and renal cysts among 2843 autopsies [corrected]. Mod Pathol 1996;9:233-7.
  • 3 Xu AM, Xian ZH, Zhang SH, Chen XF. Intrahepatic cholangiocarcinoma arising in multiple bile duct hamartomas: Report of two cases and review of the literature. Eur J Gastroenterol Hepatol 2009;21:580-4.
  • 4 Tohmé-Noun C, Cazals D, Noun R, Menassa L, Valla D, Vilgrain V, et al. Multiple biliary hamartomas: Magnetic resonance features with histopathologic correlation. Eur Radiol 2008;18:493-9.
  • 5 Desmet VJ. Congenital diseases of intrahepatic bile ducts: Variations on the theme “ductal plate malformation”. Hepatology 1992;16:1069-83.
  • 6 Karhunen PJ. Adult polycystic liver disease and biliary microhamartomas (von meyenburg's complexes). Acta Pathol Microbiol Immunol Scand A 1986;94:397-400.
  • 7 Fritz S, Hackert T, Blaker H, Hartwig W, Schneider L, Buchler MW, et al. Multiple von meyenburg complexes mimicking diffuse liver metastases from esophageal squamous cell carcinoma. World J Gastroenterol 2006;12:4250-2.
  • 8 Vitule LF, Siniuomato FM, de Melo ML, Yoshitake R. Von Meyenburg complex: Case report and literature review. Radiol Bras 2010;43:408-10.
  • 9 Sinakos E, Papalavrentios L, Chourmouzi D, Dimopoulou D, Drevelegas A, Akriviadis E. The clinical presentation of von Meyenburg complexes. Hippokratia 2011;15:170-3.
  • 10 Moorthy K, Mihssin N, Houghton PW. The management of simple hepatic cysts: Sclerotherapy or laparoscopic fenestration. Ann R Coll Surg Engl 2001;83:409-14.