Abstract
BACKGROUND: Ovarian tumors are one of the leading cancers in females with variable pathological
types. This study describes the distribution, clinical and pathological details of
various histopathological types of ovarian tumors in a tertiary care hospital in North
India.
MATERIALS AND METHODS: A retrospective data of 3 years were collected for ovarian tumors submitted to the
pathology department of a tertiary care hospital. Data were classified according to
the latest World Health Organization (WHO) Classification into epithelial tumors,
germ cell tumors, sex cord–stromal tumors, and others.
RESULTS: A total of 212 cases of ovarian tumors were studied, 186 were unilateral and 26
were bilateral. Resection specimen, part of specimen, and block review formed 80.2%,
15.1%, 4.7%, respectively. Epithelial tumors formed the majority in 71.7% of cases
followed by germ cell tumors (22.2%), sex cord–stromal tumors (3.8%) and others (2.3%).
Maximum number of cases in the respective groups occurred in the age groups 31–40,
21–30, 51–60, and 41–50 years, respectively. Overall, benign tumors were 63.7%, malignant
tumors were 31.1%, and borderline were 5.2%. The most common histopathological type
of benign and malignant tumor was benign serous cystadenoma (18.8%) and serous carcinoma
(9.9%), respectively.
CONCLUSION: In the present study, ovarian tumors were classified according to the WHO classification,
epithelial and germ cell tumors were the major types of ovarian tumors. Benign epithelial
tumor formed the majority with 46.2% cases. Serous cystadenoma and mature cystic teratoma
were the predominant type of epithelial and germ cell tumors, respectively.
Key words
Gynecologic malignancy - tumor markers - World Health Organization classification
