CC BY-NC-ND 4.0 · European Journal of General Dentistry 2013; 2(01): 8-12
DOI: 10.4103/2278-9626.106794
Review Article

Esoteric communiqué amid microbes in an oral biofilm

Harpreet Singh Grover
Department of Periodontics and Oral Implantology, SGT Dental College, Hospital and Research Institute, Gurgaon, Haryana, India
,
Shailly Luthra
Department of Periodontics and Oral Implantology, SGT Dental College, Hospital and Research Institute, Gurgaon, Haryana, India
,
Shruti Maroo
Department of Periodontics and Oral Implantology, SGT Dental College, Hospital and Research Institute, Gurgaon, Haryana, India
› Author Affiliations

Abstract

Dental biofilms are complex and multispecies ecosystems, and its formation requires coordinated chemical signaling between different micro-organisms present in the oral cavity. During the initial stages of its formation, planktonic bacterial cells directly attach to surfaces of the oral cavity or indirectly bind to other bacterial cells. This binding occurs through co-aggregation, which is critical for the temporary retention of bacteria on dental surfaces as well as bacterial colonization. It is during this colonization that the micro-organisms are able to interact with each other. In general, interspecies interactions involve communication, typically via quorum sensing, and metabolic cooperation or competition. Interactions among species within a biofilm can be antagonistic, such as competition over nutrients and growth inhibition, or synergistic. In this review, we discuss these important interactions among oral bacteria within the dental biofilm communities and novel therapies that could inhibit pathogenic micro-organisms and disrupt biofilm.



Publication History

Article published online:
01 November 2021

© 2013. European Journal of General Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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