CC BY-NC-ND 4.0 · Eur J Dent 2014; 08(02): 211-215
DOI: 10.4103/2278-344X.130603
Original Article
Dental Investigation Society

X-ray diffraction analysis of MTA-Plus, MTA-Angelus and DiaRoot BioAggregate

Yeliz Guven
1   Department of Pedodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkiye
Elif Bahar Tuna
1   Department of Pedodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkiye
Muzaffer Emin Dincol
2   Department of Endodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkiye
Oya Aktoren
1   Department of Pedodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkiye
› Author Affiliations
Further Information

Publication History

Publication Date:
25 September 2019 (online)


Objective: The purpose of this study was to investigate and compare the crystalline structures of recently released MTA Plus (MTA-P), MTA Angelus (MTA-A), DiaRoot BioAggregate (BA) by X-ray diffraction (XRD) analysis. Materials and Methods: Phase analysis was carried out on powder and set forms of tested materials. The powder specimens placed into sample holders that were packed with a glass slide and the set samples prepared according to the manufacturer's instructions were placed into molds. The samples after being set for three days at 37°C and 100% humidity in an incubator were mounted onto the XRD machine and phase identification was accomplished using a search-match software program. Results: XRD findings indicated that major constituents of MTA-P were bismuth oxide, portlandite, dicalcium silicate and tricalcium silicate. The crystal structure of MTA-A were similar to those of MTA-P except for the absence of portlandite. Additionally, MTA-A had tricalcium aluminate differing from MTA-P. BA mainly differed from MTA-P and MTA-A by the radiopacifier (tantalum oxide-TO) in its composition. Conclusions: The majority of constituents of the tested materials have shown similarity except for the presence of tricalcium aluminate in MTA-A and the inclusion of TO in BA. In addition, set MTA-P showed a strong peak of portlandite.


  • 1 Lee SJ, Monsef M, Torabinejad M. Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations. J Endod 1993; 19: 541-4
  • 2 Torabinejad M, Parirokh M. Mineral trioxide aggregate: A comprehensive literature review–part II: Leakage and biocompatibility investigations. J Endod 2010; 36: 190-202
  • 3 Fernández-Yáñez Sánchez A, Leco-Berrocal MI, Martínez-González JM. Metaanalysis of filler materials in periapical surgery. Med Oral Patol Oral Cir Bucal 2008; 13: E180-5
  • 4 Koh ET, Torabinejad M, Pitt Ford TR, Brady K, McDonald F. Mineral trioxide aggregate stimulates a biological response in human osteoblasts. J Biomed Mater Res 1997; 37: 432-9
  • 5 Song JS, Mante FK, Romanow WJ, Kim S. Chemical analysis of powder and set forms of Portland cement, gray ProRoot MTA, white ProRoot MTA, and gray MTA-Angelus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 102: 809-15
  • 6 Parirokh M, Torabinejad M. Mineral trioxide aggregate: A comprehensive literature review–part I: Chemical, physical, and antibacterial properties. J Endod 2010; 36: 16-27
  • 7 Parirokh M, Torabinejad M. Mineral trioxide aggregate: A comprehensive literature review–part III: Clinical applications, drawbacks, and mechanism of action. J Endod 2010; 36: 400-13
  • 8 Asgary S, Parirokh M, Eghbal MJ, Brink F. Chemical differences between white and gray mineral trioxide aggregate. J Endod 2005; 31: 101-3
  • 9 Camilleri J, Montesin FE, Brady K, Sweeney R, Curtis RV, Ford TR. The constitution of mineral trioxide aggregate. Dent Mater 2005; 21: 297-303
  • 10 Oliveira MG, Xavier CB, Demarco FF, Pinheiro AL, Costa AT, Pozza DH. Comparative chemical study of MTA and Portland cements. Braz Dent J 2007; 18: 3-7
  • 11 Torabinejad M, Hong CU, McDonald F, Pitt Ford TR. Physical and chemical properties of a new root-end filling material. J Endod 1995; 21: 349-53
  • 12 Camilleri J, Gandolfi MG. Evaluation of the radiopacity of calcium silicate cements containing different radiopacifiers. Int EndodJ 2010; 43: 21-30
  • 13 Park JW, Hong SH, Kim JH, Lee SJ, Shin SJ. X-Ray diffraction analysis of white ProRoot MTA and Diadent BioAggregate. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: 155-8
  • 14 Diadent DiaRoot® BioAggregate material safety data sheet. Available from: [Last accessed on 2013 Feb 10]
  • 15 Forbes WF, Gentleman JF. Risk factors, causality, and policy initiatives: The case of aluminum and mental impairment. Exp Gerontol 1998; 33: 141-54
  • 16 MTA Plus Directions for use. Available from: [Last accessed on 2013 Feb 15]
  • 17 Belío-Reyes IA, Bucio L, Cruz-Chavez E. Phase composition of ProRoot mineral trioxide aggregate by X-ray powder diffraction. J Endod 2009; 35: 875-8
  • 18 Camilleri J, Formosa L, Damidot D. The setting characteristics of MTA Plus in different environmental conditions. Int Endod J 2013; 46: 831-40
  • 19 Islam I, Chng HK, Yap AU. X-ray diffraction analysis of mineral trioxide aggregate and Portland cement. Int Endod J 2006; 39: 220-5
  • 20 Pecharsky VK, Zavalij PY. Fundamentals of Powder Diffraction and Structural Characterization of Materials. 2nd ed.. New York: Springer; 2009: p. 377-399
  • 21 Formosa LM, Mallia B, Camilleri J. Mineral trioxide aggregate with anti-washout gel-properties and microstructure. Dent Mater 2013; 29: 294-306
  • 22 Greenberg SA, Chang TN. The hydration of tricalcium silicate. J Phys Chem 1965; 69: 553-61
  • 23 Wang WH, Wang CY, Shyu YC, Liu CM, Lin FH, Lin CP. Compositional characteristics and hydration behavior of mineral trioxide aggregates. J Dent Sci 2010; 5: 53-9
  • 24 Grech L, Mallia B, Camilleri J. Characterization of set ıntermediate restorative material, biodentine, bioaggregate and a prototype calcium silicate cement for use as root-end filling materials. Int Endod J 2013; 46: 632-41
  • 25 Camilleri J. The chemical composition of mineral trioxide aggregate. J Conserv Dent 2008; 11: 141-3
  • 26 Mondal P, Jeffery JW. The crystal structure of tricalcium aluminate, Ca3Al2O6 . Acta Cryst 1975; B31: 689-97
  • 27 Steinemann SG. Titanium-the material of choice?. Periodontol 2000 1998; 17: 7-21
  • 28 Camilleri J, Montesin FE, Papaioannou S, McDonald F, Pitt Ford TR. Biocompatibility of two commercial forms of mineral trioxide aggregate. Int Endod J 2004; 37: 699-704