Download PDF
CC BY-NC-ND 4.0 · Asian J Neurosurg 2017; 12(03): 529-533
DOI: 10.4103/1793-5482.145564
ORIGINAL ARTICLE

Brain metastases in cancer patients attending a Gamma Knife Center: A study from a single institute in Iran

Parisa Azimi
Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran
,
Sohrab Shahzadi
Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran
,
Mohammad Bitaraf
1   Department of Neurosurgery, Tehran University of Medical Science, Tehran
,
Maziar Azar
1   Department of Neurosurgery, Tehran University of Medical Science, Tehran
,
Mazdak Alikhani
2   Neurosurgeon, Iran Gamma Knife Center, Tehran
,
Alireza Zali
Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran
,
Sohrab Sadeghi
Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran
,
Ali Montazeri
3   Mental Health Research Group, Health Metrics Research Centre, Iranian Institute for Health Sciences Research, ACECR, Tehran
› Author Affiliations
› Further Information
Also available at
  PDF Download Permissions and Reprints

Background: This study was aimed to explore data on brain metastases in cancer patients attending the Iranian Gamma Knife Center. Meterials and Methods: This was a retrospective study. In all 5216 case records of patients who referred to the Iranian Gamma Knife Center for treatment of brain tumors during year 2003-2011 were reviewed. Data were explored to identify patients who developed brain metastases due to cancer and assessed the information as applied to cancer patients including survival analysis. Results: Two hundred and twenty patients were identified as having brain metastases due to cancer. The mean age of patients was 54.0 (standard deviation [SD] =12.7) years. Patients were followed for an average of 7 months after treatment with gamma-knife. The median survival time for different the Graded Prognostic Assessment (GPA) was: GPA: 0-1, 4.0 ± 0.4 months; GPA: 1.5-2.5, 6.0 ± 0.7 months; GPA: 3, 9.0 ± 0.9 months; and GPA: 3.5-4.0, 12.0 ± 1.8 months and the overall median survival was 7.0 (SD = 0.6) months. Conclusion: The findings suggest that many cancer patients in Iran might develop brain metastasis. Although, this is not a very high incidence compared with the existing statistics from other countries, there is an urgent need to explore the issue further.

Key-words:

Brain metastases - epidemiology - Iran - gamma-knife


Publication History

Article published online:
20 September 2022

© 2017. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India