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CC BY-NC-ND 4.0 · World J Nucl Med 2017; 16(03): 247-250
DOI: 10.4103/1450-1147.207284
Case report

Nuclear protein in testis midline carcinoma presenting in an infant as a pericardial mass with staging by 18F-fluorodeoxyglucose-positron emission tomography/computed tomography

Crystal Perkins
Medical Student, Augusta University/University of Georgia Medical Partnership, Augusta, Georgia
,
Darko Pucar
1   Department of Radiology and Imaging, Nuclear Medicine Section, Medical College of Georgia, Augusta University, Georgia
,
Colleen McDonough
2   Department of Pediatrics, Hematology/Oncology Division, Medical College of Georgia, Augusta University, Georgia
,
Hadyn Williams
1   Department of Radiology and Imaging, Nuclear Medicine Section, Medical College of Georgia, Augusta University, Georgia
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Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, lethal, epithelioid, poorly differentiated cancerfirst described in Japan in 1991, unique in that is defined genetically rather than by histological tissue of origin. It usually arises in the body midline and presents as a mass with metastasis. An infant presenting with pneumonia was found to have a pericardial mass, NMC resected, and subsequent staging positron emission tomography (PET) showing residual mediastinal tumor and midline abdominal metastases. Fewer than 100 cases of NMC have been reported in the literature, and PET appears to be the imaging modality of choice in complete staging and evaluation of treatment response.

Keywords

18F-fluorodeoxyglucose-positron emission tomography/computed tomography - nuclear protein in testis midline carcinoma - squamous cell


Publication History

Article published online:
18 May 2022

© 2017. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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