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CC BY-NC-ND 4.0 · World J Nucl Med 2015; 14(02): 75-80
DOI: 10.4103/1450-1147.157120
Review article

Advances in SPECT for Optimizing the Liver Tumors Radioembolization Using Yttrium-90 Microspheres

Hoda Roshan
Department of Medical Physics, Nuclear Medicine Unit, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
,
Ahmadreza Azarm
Department of Medical Physics, Nuclear Medicine Unit, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
,
Babak Mahmoudian
1   Department of Radiology, Nuclear Medicine Unit, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
,
Jalil Islamian
Department of Medical Physics, Nuclear Medicine Unit, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Radioembolization (RE) with Yttrium-90 ( 90 Y) microspheres is an effective treatment for unresectable liver tumors. The activity of the microspheres to be administered should be calculated based on the type of microspheres. Technetium-99m macroaggregated albumin ( 99m Tc-MAA) single photon emission computed tomography/computed tomography (SPECT/CT) is a reliable assessment before RE to ensure the safe delivery of microspheres into the target. 90 Y bremsstrahlung SPECT imaging as a posttherapeutic assessment approach enables the reliable determination of absorbed dose, which is indispensable for the verification of treatment efficacy. This article intends to provide a review of the methods of optimizing 90 Y bremsstrahlung SPECT imaging to improve the treatment efficacy of liver tumor RE using 90 Y microspheres.

Keywords

Bremsstrahlung SPECT - radioembolization - single photon emission computed tomography/computed tomography - Yttrium-90 microspheres


Publication History

Article published online:
21 May 2022

© 2015. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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