CC BY-NC-ND 4.0 · Journal of Digestive Endoscopy 2016; 07(04): 137-143
DOI: 10.4103/0976-5042.195739
Original Article
Journal of Digestive Endoscopy

Nonfluoroscopic endoscopic ultrasound-guided transmural drainage of pancreatic pseudocysts at atypical locations

Surinder Singh Rana
Departments of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Vishal Sharma
Departments of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Ravi Sharma
Departments of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Puneet Chhabra
Departments of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Rajesh Gupta
1   Department of Gastroenterology, Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Deepak Kumar Bhasin
Departments of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations
Further Information

Publication History

Publication Date:
26 September 2019 (online)

Abstract

Background: Pancreatic pseudocysts (PP) at atypical locations are a therapeutic challenge and are usually managed surgically. Objective: We evaluated safety and efficacy of nonfluoroscopic endoscopic ultrasound (NF-EUS)-guided transmural drainage in the management of PP at atypical locations. Patients and Methods: Retrospective analysis of 11 patients (all males; age range: 28–46 years) with PP at atypical locations who were treated with NF-EUS-guided transmural drainage during the last 18 months was done. Results: Four patients had intra/peri-splenic, three patients had mediastinal, three patients had intrahepatic, and one patient had renal PP. Nine patients had chronic pancreatitis whereas two patients had acute pancreatitis. Alcohol was the etiology of pancreatitis in ten patients. The size of PP ranged from 4 to 10 cm. All patients had abdominal pain, and two patients had fever whereas one patient with mediastinal PP also had dysphagia. NF-EUS-guided transmural drainage could be done successfully in all patients. 7 Fr transmural stent(s) was/were placed in six patients whereas single-time complete aspiration of PP was done in five patients. On endoscopic retrograde pancreatography, six patients had partial duct disruption whereas five patients had complete disruption. Bridging transpapillary stent (5 Fr) was placed in all patients with partial disruption. All PP healed in 10/11 (91%) patients within 2–4 weeks, and there has been no recurrence in 9 of these patients during a follow-up period of 4–18 months. One patient with splenic PP needed surgery for gastrointestinal bleed. Conclusion: PP at atypical locations can be effectively and safely treated with NF-EUS-guided transmural drainage.

 
  • References

  • 1 Lehman GA. Pseudocysts. Gastrointest Endosc 1999;49(3 Pt 2):S81-4.
  • 2 Baron TH. Endoscopic drainage of pancreatic pseudocysts. J Gastrointest Surg 2008;12:369-72.
  • 3 Bhasin DK, Rana SS, Chandail VS, Nanda M, Nadkarni N, Sinha SK, et al. An intra-hepatic pancreatic pseudocyst successfully treated endoscopic transpapillary drainage alone. JOP 2005;6:593-7.
  • 4 Bhasin DK, Rana SS, Chandail VS, Nanda M, Sinha SK, Nagi B. Successful resolution of a mediastinal pseudocyst and pancreatic pleural effusion by endoscopic nasopancreatic drainage. JOP 2005;6:359-64.
  • 5 Gandhi M, Barone JG. Pediatric renal pseudocyst due to pancreatitis. Urology 2006;68:1344.e5-6.
  • 6 Bhasin DK, Rana SS, Nanda M, Chandail VS, Masoodi I, Kang M, et al. Endoscopic management of pancreatic pseudocysts at atypical locations. Surg Endosc 2010;24:1085-91.
  • 7 Bhasin DK, Rana SS, Rao C, Gupta R, Kang M, Sinha SK, et al. Clinical presentation, radiological features, and endoscopic management of mediastinal pseudocysts: Experience of a decade. Gastrointest Endosc 2012;76:1056-60.
  • 8 Balzan S, Kianmanesh R, Farges O, Sauvanet A, O’toole D, Levy P, et al. Right intrahepatic pseudocyst following acute pancreatitis: An unusual location after acute pancreatitis. J Hepatobiliary Pancreat Surg 2005;12:135-7.
  • 9 Johnston RH Jr., Owensby LC, Vargas GM, Garcia-Rinaldi R. Pancreatic pseudocyst of the mediastinum. Ann Thorac Surg 1986;41:210-2.
  • 10 Guenther L, Hardt PD, Collet P. Review of current therapy of pancreatic pseudocysts. Z Gastroenterol 2015;53:125-35.
  • 11 Binmoeller KF, Seifert H, Walter A, Soehendra N. Transpapillary and transmural drainage of pancreatic pseudocysts. Gastrointest Endosc 1995;42:219-24.
  • 12 Yang D, Amin S, Gonzalez S, Mullady D, Hasak S, Gaddam S, et al. Transpapillary drainage has no added benefit on treatment outcomes in patients undergoing EUS-guided transmural drainage of pancreatic pseudocysts: A large multicenter study. Gastrointest Endosc 2016;83:720-9.
  • 13 Mofredj A, Cadranel JF, Dautreaux M, Kazerouni F, Hadj-Nacer K, Deplaix P, et al. Pancreatic pseudocyst located in the liver: A case report and literature review. J Clin Gastroenterol 2000;30:81-3.
  • 14 Shenoy P, Ganesan P, Swaminathan RP. Systemic hypertension due to compression of the kidney by a pancreatic pseudocyst. Eur J Intern Med 2007;18:507-8.
  • 15 Mohl W, Moser C, Kramann B, Zeuzem S, Stallmach A. Endoscopic transhiatal drainage of a mediastinal pancreatic pseudocyst. Endoscopy 2004;36:467.
  • 16 Saftoiu A, Ciurea T, Dumitrescu D, Stoica Z. Endoscopic ultrasound-guided transesophageal drainage of a mediastinal pancreatic pseudocyst. Endoscopy 2006;38:538-9.
  • 17 Sugimoto S, Yamagishi Y, Higuchi H, Kanai T. Endoscopic ultrasound-guided drainage for a mediastinal pancreatic pseudocyst. Intern Med 2014;53:2651-2.
  • 18 Kawakami H, Itoi T, Sakamoto N. Endoscopic ultrasound-guided transluminal drainage for peripancreatic fluid collections: Where are we now? Gut Liver 2014;8:341-55.
  • 19 Rana SS, Bhasin DK. Nonfluoroscopic endoscopic ultrasound-guided transmural drainage of pseudocysts: A pictorial technical review. Endosc Ultrasound 2015;4:92-7.
  • 20 Rana SS, Bhasin DK, Rao C, Gupta R, Singh K. Non-fluoroscopic endoscopic ultrasound-guided transmural drainage of symptomatic non-bulging walled-off pancreatic necrosis. Dig Endosc 2013;25:47-52.
  • 21 Ueda N, Takahashi N, Yamasaki H, Hirano K, Ueda K, Yoshida S, et al. Intrasplenic pancreatic pseudocyst: A case report. Gastroenterol Jpn 1992;27:675-82.
  • 22 Bhasin DK, Udawat HP, Rana SS, Sood AK, Sinha SK, Nagi B. Intrasplenic pancreatic abscess successfully treated by endoscopic transpapillary drainage through the minor papilla. Gastrointest Endosc 2005;62:192-4.
  • 23 Trevino JM, Tamhane A, Varadarajulu S. Successful stenting in ductal disruption favorably impacts treatment outcomes in patients undergoing transmural drainage of peripancreatic fluid collections. J Gastroenterol Hepatol 2010;25:526-31.
  • 24 Lo J, Tang S. CT of multiple subcapsular pseudocysts of the kidney complicating acute pancreatitis. J Comput Assist Tomogr 1995;19:823-4.
  • 25 Rana SS, Bhasin DK, Rao C, Sharma R, Gupta R. Consequences of long term indwelling transmural stents in patients with walled off pancreatic necrosis and disconnected pancreatic duct syndrome. Pancreatology 2013;13:486-90.
  • 26 Rana SS, Sharma R, Sharma V, Chhabra P, Gupta R, Bhasin DK. Prevention of recurrence of fluid collections in walled off pancreatic necrosis and disconnected pancreatic duct syndrome: Comparative study of one versus two long term transmural stents. Pancreatology 2016;16:687-8.
  • 27 Rana SS, Bhasin DK, Sharma R, Gupta R. Factors determining recurrence of fluid collections following migration of intended long term transmural stents in patients with walled off pancreatic necrosis and disconnected pancreatic duct syndrome. Endosc Ultrasound 2015;4:208-12.