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CC BY-NC-ND 4.0 · J Lab Physicians 2010; 2(02): 111-113
DOI: 10.4103/0974-2727.72214
Case Report

Epithelioid Hemangioendothelioma of Nasal Cavity

Rashmi Patnayak
Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
,
Amitabh Jena
Department of Surgical Oncology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
,
M Kumaraswamy Reddy
Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
,
Amit kumar Chowhan
Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
,
LM Chandrasekhar Rao
Department of Surgical Oncology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
,
N Rukhamangadha
Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
› Author Affiliations Source of Support: Nil
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ABSTRACT

We present a rare case of epithelioid hemangioendothelioma (EHE) in the nasal cavity of a 40-year-old Indian male who presented with history of intermittent epistaxis. The lesion was tested for a panel of immunohistochemical markers like vimentin, CD31, CD34, Factor VIII, vascular endothelial growth factor (VEGF) and Ki67. Immunohistochemically, the neoplasm showed striking positivity for vimentin, CD31, CD34 and weak positivity for VEGF; positivity was also noted for Factor VIII especially in the miniature intracytoplasmic vascular lumina.

Keywords

Epithelioid hemangioendothelioma - nasal cavity - immunohistochemistry


Publication History

Article published online:
29 January 2020

© 2010.

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