Download PDF
CC BY-NC-ND 4.0 · J Lab Physicians 2013; 5(02): 139-141
DOI: 10.4103/0974-2727.119875
Case Report

Periampullary Adenocarcinoid: Diagnostic Dilemma

Rashmi Krishnappa
Department of Pathology, M S Ramaiah Medical College and Teaching Hospital, Bangalore, India
,
Sudha Horakerappa Metikurke
Department of Pathology, M S Ramaiah Medical College and Teaching Hospital, Bangalore, India
,
Sridhar Honnappa
Department of Pathology, M S Ramaiah Medical College and Teaching Hospital, Bangalore, India
,
Rudresh Hosakote
Department of General Surgery, M S Ramaiah Medical College and Teaching Hospital, Bangalore, India
,
Nagesh Kumar Talkad Chandrashekar
Department of General Medicine, M S Ramaiah Medical College and Teaching Hospital, Bangalore, India
› Author Affiliations
Source of Support: Nil.
› Further Information
Also available at
 PDF Download Permissions and Reprints

ABSTRACT

The growth in periampullary region needs proper evaluation as they can arise from duodenum, pancreas and extra hepatic biliary tree. We have reported a case of adenocarcinoid of duodenum presenting as periampullary growth with obstructive jaundice. Histologically, tumor displayed biphasic pattern, i.e. tubuloglandular architecture with admixed sheets of neuroendocrine cells without pancreas and extra hepatic biliary tree involvement. The adenocarcinoids are of great diagnostic challenges for the pathologist interpreting endoscopic biopsy for the frequent misinterpretation as negative due to their submucosal location or as adenocarcinomas due to tubulo-glandular architecture.

Keywords

Adenocarcinoids - carcinoids - periampullary region


Publication History

Article published online:
07 April 2020

© 2013.

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

  • REFERENCES

  • 1 Costantini M, Montalti R, Rossi G, Luisa L, Masetti M, Di Benedetto F, et al. Adenocarcinoids tumor of extra hepatic biliary tree. Int J Surg Pathol 2008;16:455-57.
  • 2 Levy AD, Taylor LD, Abboth RM, Sobin LH. Duodenal carcinoids: Imaging features with clinical - pathological comparison. Radiology 2005;237:967-72.
  • 3 Levendoglu H, Cox CA, Nadimpalli V. Composite (adenocarcinoid) tumor of gastrointestinal tract. Dig Dis Sci 1990;35:519-25.
  • 4 Hatzitheoklitos E, Buchler MW, Friess H, Poch B, Ebert M, Mohr W, et al. Carcinoids of ampulla of vater. Clinical characteristics and morphological features. Cancer 1994;73:1580-8.
  • 5 Ferrando Marco J, Pallas Regueira A, Moro Valdezate D, Fernandez Martinez C. Collision tumor of the ampulla of Vater: Carcinoid and adenocarcinoma. Rev Esp Enferm Dig 2007;99:235-8.
  • 6 Jess RJ. Tumor of small and large intestine. In: Fletcher CDM, editor. Diagnostic histopathology of tumors, 3rd ed. China: Churchill Livingston Elselvier; 2007. p. 379-416.