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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2011; 32(04): 233-237
DOI: 10.4103/0971-5851.95149
CASE REPORT

Rare metastatic prostatic malignancy: A case report and approach to management

M Vamshi Krishna
Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
,
Kumar Prabhash
Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
,
Vanita Noronha
Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
,
Santosh Menon
Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, India
,
Sumeet Dua
Department of Nuclear Medicine, Tata Memorial Hospital, Parel, Mumbai, India
,
V Rangarajan
Department of Nuclear Medicine, Tata Memorial Hospital, Parel, Mumbai, India
,
H B Tangaonkar
Department of Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
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Abstract

We present a patient with metastatic leiomyosarcoma of the prostate who achieved complete response with chemotherapy. A 70 years old male patient presented with urinary tract symptoms and a prostatic mass. After having been treated as carcinoma prostate, he presented with progressive pelvic mass, lung and bone metastases to our hospital. Repeat biopsy was suggestive of prostatic leiomyosarcoma. He was treated with chemotherapy with the ifosfamide-epirubicin regimen and achieved complete remission on positron emission tomography/computerized tomography after three cycles. He was given a total of six cycles of chemotherapy and continues to be disease-free after 8 months. Although adenocarcinomas are the commonest prostatic malignancies in the elderly, a careful evaluation is essential to rule out alternative diagnoses. Our case report illustrates the potential role of combination chemotherapy in the management of advanced leiomyosarcoma of the prostate. The literature on this entity is reviewed.

Keywords

Chemotherapy - leiomyosarcoma - positron emission tomography/computerized tomography - prostate


Publication History

Article published online:
06 August 2021

© 2011. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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