Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2011; 32(02): 82-85
DOI: 10.4103/0971-5851.89778
ORIGINAL ARTICLE

Bone tumors in a tertiary care hospital of south India: A review 117 cases

Karun Jain
Department of Orthopaedics, JSSMC, Mysore, Karnataka, India
,
Sunila,
R Ravishankar
Department of Orthopaedics, JSSMC, Mysore, Karnataka, India
,
Mruthyunjaya,
C S Rupakumar
Department of Orthopaedics, JSSMC, Mysore, Karnataka, India
,
H B Gadiyar
Department of Orthopaedics, JSSMC, Mysore, Karnataka, India
,
G V Manjunath
Department of Pathology, JSSMC, Mysore, Karnataka, India
› Author Affiliations Source of Support Nil.
› Further Information
  PDF Download Permissions and Reprints

Abstract

Background: Bone tumors remain a daunting challenge to orthopedic surgeons. The challenge is heightened in developing countries due to limited diagnostic and therapeutic facilities as well as due to ignorance. The published literature on this subject is sparse in our environment. Objective: To determine the pattern of bone tumors including their relative frequencies, age and sex distributions, anatomical sites of occurrence and clinico-pathological characteristics as seen in a tertiary care hospital of south India. Materials and Methods: This is a retrospective review of all the histologically confirmed bone tumors seen at JSS Medical College and Hospital, Mysore over an 8 year period: 2002 to 2009. Results: A total of 117 patients (aged 5 to 82 years) with a mean of age of 26.87 years were studied. Seventy-six patients (64.96%) were males and 41 (35.04%) were females. The peak age incidence for primary bone tumors was in the age group of 11-20 years and that for metastatic bone tumors was more than 60 years. Sixty-seven (57.26%) of the tumors were benign. Among these, osteochondroma was the most common, accounting for 26 cases (22.22%) followed by Giant cell tumor (24 cases, 20.51%). Osteosarcoma accounted for 35.14% (13 cases) of all the primary malignant tumors in the study. Lower end of femur was the most common site for primary bone tumors and accounted for 30 cases (25.64%) followed by upper end of tibia and fibula (24 cases, 20.51%). The most common site for metastatic bone tumors was upper end of femur including hip joint followed by spine. Conclusion: This study showed that primary bone tumors are mainly benign, occurred predominantly in the second decade of life with a male preponderance. Osteochondroma and osteosarcoma are the most common benign and primary malignant bone tumors, respectively. The most common primary foci for metastatic bone tumor are from the respiratory tract.

Keywords

Bone tumors - giant cell tumor - metastasis - osteosarcoma - osteochondroma


Publication History

Article published online:
06 August 2021

© 2011. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Mohammed A, Sani MA, Hezekiah IA, Enoch AA. Primary bone tumours and tumour-like lesions in children in Zaria, Nigeria. Afr J Paediatr Surg 2010;7:16-8.
  • 2 Fletches CD, Unni KK, Mertens F, editors. World Health Organisation Classification of Tumors. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: 1ARC Press; 2002.
  • 3 Omololu AB, Ogunbiyi JO, Ogunlade SO, Alonge TO, Adebisi A, Akang EE. Primary malignant bone tumours in Ibadan. West Afr J Med 2002;21:201-3.
  • 4 Mohammed A, Isa HA. Patterns of primary tumours and tumour like lesions of bone in Zaria. Northern Nigeria: A review of 127 cases. West Afr J med 2007;26:37-41.
  • 5 Senac MO Jr, Isaacs H, Gwinn JL. Primary Lesions of bone in 1 st decade of life: Retrospective survey of biopsy result. Radiology 1986;160:491-5.
  • 6 Rai KM, Venkateswarlu S. Osteoclastoma. Indian J Radiol Imaging 2008;18:4-11.
  • 7 Bone RJ, Joints. In: Rosai J, editor. Ackerman′s Surgical Pathology. St. Louis: Mosby; 1996. p. 1917-2020.
  • 8 Aston W, Briggs T, Solomon L. Tumors. In: Solomon L, Warwick D, Nayagam S, editors. Apley′s System of Orthopaedics and Fractures. 9 th ed. London: Hodder Arnold, Hodder education; 2010. p. 187-224.
  • 9 Rosenberg AE. Bones, joints and soft tissue tumors. In: Kumar V, Abbas AK, Fausto N, Aster JC, editors. Robbins and cotran; Pathologic Basis of disease. 8 th ed. Gurgaon: Elsevier, Reed Elsevier India private limited; 2010. p. 1205-56.
  • 10 Bahebeck J, Atangana R, Eyenga V, Pisoh A, Sando Z, Hoffmeyer P. Bone tumours in Cameroon: Incidence, demography and histopathology. Int Orthop 2003;27:315-7.
  • 11 Xu DL , Zhang XT , Wang GH , Li FB , Hu JY . Clinical features of pathologically confirmed metastatic bone tumors--a report of 390 cases.[Article in Chinese]. Ai Zheng 2005;11:1404-7.