CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2009; 30(04): 141-143
DOI: 10.4103/0971-5851.65338

Mesenchymal hamartoma of the liver

Rahul Gupta
Department of Pediatric Surgery, King Edward Memorial Hospital, Parel, Mumbai, India
Sandesh V Parelkar
Department of Pediatric Surgery, King Edward Memorial Hospital, Parel, Mumbai, India
Beejal Sanghvi
Department of Pediatric Surgery, King Edward Memorial Hospital, Parel, Mumbai, India
› Author Affiliations


Mesenchymal hamartoma of the liver is the second most common benign liver tumor in children, yet its biology and pathogenesis are poorly understood. Typically, it presents as a large benign multicystic liver mass in children younger than three years, amenable to complete resection. Most tumors gradually increase in size, some reaching enormous proportions, some can undergo incomplete spontaneous regression, and rarely, few have shown malignant transformation to undifferentiated (embryonal) sarcoma. Here, we report a 13 month-old child who presented with abdominal distension and respiratory distress. Ultrasonography, Computed Tomography (CT), and magnetic resonance imaging (MRI) of the abdomen were suggestive of a mesenchymal hamartoma of the liver. Right hepatectomy was performed. Postoperatively, the patient recovered well. An attempt was also made to understand the possible etiology of the tumor.

Publication History

Article published online:
19 November 2021

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  • References

  • 1 Stocker JT, Ishak KG. Mesenchymal hamartoma of the liver: Report of 30 cases and review of the literature. Pediatr Pathol 1983;1:245-67.
  • 2 Kirks DR, Griscom NT, editors. Practical pediatric imaging: Diagnostic radiology of infants and children. 3 rd ed. Lippincott Williams and Wilkins. Boston: Little, Brown; 1990. p. 808-15.
  • 3 Edmondson HA. Differential diagnosis of tumors and tumor-like lesions of the liver in infancy and childhood. AMA J Dis Child 1956;91:168-86.
  • 4 Dehner LP, Ewing SL, Sumner HW. Infantile mesenchymal hamartoma of the liver. Arch Pathol 1975;99:379-82.
  • 5 Packard GB, Palmer HD. Primary neoplasm of the liver in infants and children. Ann Surg 1955;142:214-27.
  • 6 Ito H, Kishikawa T, Toda T, Arai M, Muro H. Hepatic mesenchymal hamartoma of an infant. J Pediatr Surg 1984;19:315-7.
  • 7 Luks FI, Yazbeck S, Brandt ML, Bensoussan AL, Brochu P, Blanchard H. Benign liver tumors in children: A 25 year experience. J Pediatr Surg 1991;126:1326-30.