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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(01): 88-89
DOI: 10.4103/0971-5851.203509
Practitioner Section

Squamous Cell Carcinoma In situ of the Cervix with Superficial Intraepithelial Extension to the Endometrium of Lower Uterine Segment: A Rare Presentation

Rajeshwari K Muthusamy
Department of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, India
,
Sangita S Mehta
Department of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, India
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Abstract

Carcinoma of the cervix is the most common malignancy in women in India. Squamous cell carcinoma accounts for more than 70% of the cervical malignancies. Carcinoma of the cervix generally invades the uterine wall by direct extension with or without parametrial involvement, however, rarely can spread superficially to the inner surface of the uterus replacing the endometrium. It is an uncommon phenomenon for an in situ lesion of the cervix to have contiguous superficial spread to the endometrium. We report a case of cervical in situ squamous cell carcinoma in a 45-year-old female with contiguous extension to the endometrium of the lower uterine segment.

Keywords

Carcinoma in situ - carcinoma of cervix - CD138 - lower uterine segment - superficial spreading


Publication History

Article published online:
06 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Agashe SR, Kulkarni MP, Momin YA, Sulhyan KR. Superficial extension of squamous cell carcinoma in situ of cervix involving endometrium, bilateral fallopian tubes and ovaries: A case report. Indian J Pathol Microbiol 2007;50:375-7.
  • 2 Tan GC, Isa MR, Ng SP, Jamil YM. Unusual form of superficial spreading microinvasive squamous cell carcinoma of uterine cervix involving the endometrium of uterus. J Obstet Gynaecol Res 2004;30:363-7.
  • 3 Gupta S, Gupta IM, Tiwari PV. In-situ carcinoma of the uterine cervix showing superficial endometrial spread. Acta Obstet Gynecol Scand 1979;58:507-8.
  • 4 Kushima M, Fujii H, Murakami K, Ota H, Matsumoto T, Motoyama T, et al. Simultaneous squamous cell carcinomas of the uterine cervix and upper genital tract: Loss of heterozygosity analysis demonstrates clonal neoplasms of cervical origin. Int J Gynecol Pathol 2001;20:353-8.
  • 5 Pins MR, Young RH, Crum CP, Leach IH, Scully RE. Cervical squamous cell carcinoma in situ with intraepithelial extensions to the upper genital tract and invasion of tubes and ovaries: Report of a case with human papilloma virus analysis. Int J Gynacol Pathol 1997;16:272-8.
  • 6 Gungor T, Altinkaya SO, Ozat M, Akbay S, Mollamahmutoglu L. Unusual form of superficial spreading squamous cell carcinoma of cervix involving the endometrium, bilateral tubes and ovaries: A case report with literature review. Arch Gynecol Obstet 2011;283:323-7.
  • 7 Ishida M, Okabe H. Superficial spreading squamous cell carcinoma of the uterine cervix involving the endometrium: Report of two cases with emphasis on the likely molecular mechanism. Oncol Lett 2013;5:31-4.