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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2016; 37(04): 265-270
DOI: 10.4103/0971-5851.195742
ORIGINAL ARTICLE

Evaluation of thyroid lesions by fine-needle aspiration cytology based on Bethesda system for reporting thyroid cytopathology classification among the population of South Bihar

Richa Bhartiya
Department of Pathology, Patna Medical College and Hospital, Patna, Bihar, India
,
Mahasweta Mallik
Department of Pathology, Patna Medical College and Hospital, Patna, Bihar, India
,
Nawanita Kumari
Department of Pathology, Patna Medical College and Hospital, Patna, Bihar, India
,
Brijendra Narayan Prasad
Department of Pathology, Patna Medical College and Hospital, Patna, Bihar, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Background: Fine-needle aspiration (FNA) of the thyroid gland has proven to be an important and widely accepted, cost-effective, simple, safe, and accurate method triaging patients with thyroid nodules. Awareness and understanding of wide spectrum thyroid disorders are of great value because most lesions are treatable by medical or surgical management. Aim: The aim of this study is to determine the accuracy of FNA cytology (FNAC) in the diagnosis of thyroid lesion using the Bethesda system for reporting thyroid cytopathology nomenclature (BSRTC) and to correlate these with histopathological findings. Materials and Methods: FNA was performed in 238 patients from January 2014 to October 2015 at a Tertiary Teaching Hospital in Bihar presenting with the thyroid swelling and its histopathological correlation was done in 105 patients. Results and Observations: Out of 238 patients with thyroid swelling, majority were females (196) and in younger age group (n = 104 [43.6%], 21–40 years). In 224 cases, adequate smears for cytological interpretation were obtained. Among them, colloid goiter was the most common lesion. Of these, 105 cases were surgically treated, and tissue was submitted for histopathological examination, which showed 97 nonneoplastic lesions and eight neoplastic lesions. Conclusion: FNAC is rapid, simple, safe, and cost-effective diagnostic modality in the investigation of thyroid disease with high sensitivity, specificity, and accuracy. It can be used as an excellent first-line method for investigating the nature of lesion. Bethesda system is very useful as it is simplified, systematic, standardized system for reporting thyroid cytopathology, which provides better communication between cytopathologist and clinicians, leading to more consistent management approach.

Keywords

Bethesda nomenclature - colloid goiter - follicular neoplasm - papillary carcinoma thyroid - thyroiditis


Publication History

Article published online:
12 July 2021

© 2016. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Hamberger B, Gharib H, Melton LJ 3rd, Goellner JR, Zinsmeister AR. Fine-needle aspiration biopsy of thyroid nodules. Impact on thyroid practice and cost of care. Am J Med 1982;73:381-4.
  • 2 Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 2006;295:2164-7.
  • 3 Yassa L, Cibas ES, Benson CB, Frates MC, Doubilet PM, Gawande AA, et al. Long-term assessment of a multidisciplinary approach to thyroid nodule diagnostic evaluation. Cancer 2007;111:508-16.
  • 4 Jo VY, Stelow EB, Dustin SM, Hanley KZ. Malignancy risk for fine-needle aspiration of thyroid lesions according to the Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol 2010;134:450-6.
  • 5 Baloch Z, Layfield LJ. Quest for a uniform cyto-diagnostic approach to thyroid aspirates: A consensus proposal. Diagn Cytopathol 2006;34:85-6.
  • 6 Lewis CM, Chang KP, Pitman M, Faquin WC, Randolph GW. Thyroid fine-needle aspiration biopsy: Variability in reporting. Thyroid 2009;19:717-23.
  • 7 Baloch ZW, LiVolsi VA, Asa SL, Rosai J, Merino MJ, Randolph G, et al. Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: A synopsis of the National Cancer Institute Thyroid fine-needle aspiration state of the science conference. Diagn Cytopathol 2008;36:425-37.
  • 8 Baloch ZW, Cibas ES, Clark DP, Layfield LJ, Ljung BM, Pitman MB, et al. The National Cancer Institute thyroid fine needle aspiration state of the science conference: A summation. Cytojournal 2008;5:6.
  • 9 Cibas ES, Ali SZ; NCI Thyroid FNA State of the Science Conference. The Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol 2009;132:658-65.
  • 10 Handa U, Garg S, Mohan H, Nagarkar N. Role of the fine-needle aspiration cytology in diagnosis and management of thyroid lesions. A study on 434 patients. J Cytol 2008;25:13-7.
  • 11 Ali SZ. Thyroid cytopathology: Bethesda and beyond. Acta Cytol 2011;55:4-12.
  • 12 Guidelines of the Papanicolaou Society of Cytopathology for fine-needle aspiration procedure and reporting. The papanicolaou society of cytopathology task force on standards of practice. Diagn Cytopathol 1997;17:239-47.
  • 13 Yang J, Schnadig V, Logrono R, Wasserman PG. Fine-needle aspiration of thyroid nodules: A study of 4703 patients with histologic and clinical correlations. Cancer 2007;111:306-15.
  • 14 Orell SR, Sterrett GF, Whitaker D. Thyroid. In: Fine Needle Aspiration Cytology. 4th ed. Philadelphia: Churchill Livingstone; 2005. p. 125-64.
  • 15 Baloch ZW, Tam D, Langer J, Mandel S, LiVolsi VA, Gupta PK. Ultrasound-guided fine-needle aspiration biopsy of the thyroid: Role of on-site assessment and multiple cytologic preparations. Diagn Cytopathol 2000;23:425-9.