CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2015; 36(02): 123-127
DOI: 10.4103/0971-5851.158846
ORIGINAL ARTICLE

Role of triple test score in the evaluation of palpable breast lump

Smita Sushil Kachewar
Department of Pathology, Smt. Kashibai Navale Medical College and General Hospitals, Narhe, Ambegaon, Pune, India
,
Suryakant Dattatraya Dongre
Department of Pathology, Rural Medical College, PIMS (DU), Loni-Bk., Ahmednagar, Maharashtra, India
› Author Affiliations

Abstract

Introduction: Fine-needle aspiration cytology (FNAC) method is safe, reliable and time saving outdoor procedure with little discomfort to the patient for detecting Carcinoma breast. The efficacy can further be enhanced when physical breast examination, mammography and FNAC (the triple test [TT]) are jointly taken into consideration. Aims and Objectives : The aim was to evaluate the role of TT score (TTS) in palpable breast masses. Materials and Methods: This prospective study was carried out from May 2010 to April 2012. In the subjects referred to the Department of Pathology for FNAC of the breast mass, the TTS was calculated, and histopathological findings were noted. Results: In the study period TTS score was calculated in 200 cases out of 225 FNAC′s of breast. Of 124 benign cases on cytology, only three showed discordant TTS. Out of 62 malignant cases, 61 showed concordant TTS and one case of mastitis on histopathology showed TTS of five. Out of all the benign lesions, two cases of fibrocystic disease and a single case of phylloides tumor gave a TTS ≥6. These cases were diagnosed as infiltrating ductal carcinoma and angiosarcoma respectively on histopathology. Histopathological correlation was possible in only 70 patients. Of these 70, 28 were from the benign category and 42 were from the malignant category. TTS of ≥6 has a sensitivity of 97.44%, specificity of 100%. FNAC has a sensitivity of 88.37%, specificity of 96.42%. Conclusions: TT reliably guides evaluation of palpable breast masses. Histological correlation indicated TTS to be better diagnostic tool than FNAC alone.



Publication History

Article published online:
12 July 2021

© 2015. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Chopra R. The Indian scene. J Clin Oncol 2001;19:106S-11.
  • 2 Pant I, Singh PK, Singh SN, Agarwal A, Singh NB. Cyto morphological study of palpable breast lesion and histopathologic correlation. J Cytol 2003;20:129-32.
  • 3 Meena SP, Hemrajani DK, Joshi N. A comparative and evaluative study of cytological and histological grading system profile in malignant neoplasm of breast - An important prognostic factor. Indian J Pathol Microbiol 2006;49:199-202.
  • 4 Lester SC. The breast. In: Kumar V, Abbas AK, Aster JC, Fausto N, editors. Robins and Cotran Pathologic Basis of Disease. 8 th ed., Vol. 23. Philadelphia: Saunders an Imprint of Elsevier 2010; p. 1068-9.
  • 5 Morris A, Pommier RF, Schmidt WA, Shih RL, Alexander PW, Vetto JT. Accurate evaluation of palpable breast masses by the triple test score. Arch Surg 1998;133:930-4.
  • 6 Rubin M, Horiuchi K, Joy N, Haun W, Read R, Ratzer E, et al. Use of fine needle aspiration for solid breast lesions is accurate and cost-effective. Am J Surg 1997;174:694-6.
  • 7 Somers RG, Sandler GL, Kaplan MJ, Najjar D, Anderson AV, Cohen MH. Palpable abnormalities of the breast not requiring excisional biopsy. Surg Gynecol Obstet 1992;175:325-8.
  • 8 Morris KT, Pommier RF, Morris A, Schmidt WA, Beagle G, Alexander PW, et al. Usefulness of the triple test score for palpable breast masses. Arch Surg 2001;136:1008-12.
  • 9 Tabbara SO, Frost AR, Stoler MH, Sneige N, Sidawy MK. Changing trends in breast fine-needle aspiration: Results of the Papanicolaou Society of Cytopathology Survey. Diagn Cytopathol 2000;22:126-30.
  • 10 Ghafouri A, Attarian SH, Tavangar M, Sedighi N. Modified triple test score (MTTS) for evaluation of palpable breast masses in women under age 40. Med J Islam Repub Iran 2006;20:115-8.
  • 11 Vetto J, Pommier R, Schmidt W, Wachtel M, DuBois P, Jones M, et al. Use of the "triple test" for palpable breast lesions yields high diagnostic accuracy and cost savings. Am J Surg 1995;169:519-22.
  • 12 Hermansen C, Skovgaard Poulsen H, Jensen J, Langfeldt B, Steenskov V, Frederiksen P, et al. Diagnostic reliability of combined physical examination, mammography, and fine-needle puncture ("triple-test") in breast tumors. A prospective study. Cancer 1987;60:1866-71.
  • 13 Choi YD, Choi YH, Lee JH, Nam JH, Juhng SW, Choi C. Analysis of fine needle aspiration cytology of the breast: A review of 1,297 cases and correlation with histologic diagnoses. Acta Cytol 2004;48:801-6.
  • 14 Park IA, Ham EK. Fine needle aspiration cytology of palpable breast lesions. Histologic subtype in false negative cases. Acta Cytol 1997;41:1131-8.
  • 15 Mohammed AZ, Edino ST, Ochicha O, Alhassan SU. Value of fine needle aspiration biopsy in preoperative diagnosis of palpable breast lumps in resource-poor countries: A Nigerian experience. Ann Afr Med 2005;4:19-22.
  • 16 Kim A, Lee J, Choi JS, Won NH, Koo BH. Fine needle aspiration cytology of the breast. Experience at an outpatient breast clinic. Acta Cytol 2000;44:361-7.
  • 17 Sankaye SB, Dongre SD. Cytological study of palpable breast lumps presenting in an Indian rural setup. Indian J Med Paediatr Oncol 2014;35:159-64.