Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2014; 35(04): 235-236
DOI: 10.4103/0971-5851.144959
EDITORIAL

Timing of surgery following chemoradiotherapy in rectal Cancer

Gina Brown
Department of Radiology, Royal Marsden NHS Foundation Trust Sutton, Surrey, SM2 5PT, Sutton, United Kingdom
,
Jessica Evans
Department of Radiology, Royal Marsden NHS Foundation Trust Sutton, Surrey, SM2 5PT, Sutton, United Kingdom
› Author Affiliations
› Further Information
  PDF Download Permissions and Reprints


Publication History

Article published online:
19 July 2021

© 2014. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Evans J, Tait D, Swift I, Pennert K, Tekkis P, Wotherspoon A, et al. Timing of surgery following preoperative therapy in rectal cancer: The need for a prospective randomized trial? Dis Colon Rectum 2011;54:1251-9.
  • 2 Francois Y, Nemoz CJ, Baulieux J, Vignal J, Grandjean JP, Partensky C, et al. Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: The Lyon R90-01 randomized trial. J Clin Oncol 1999;17:2396.
  • 3 Johnston DF, Lawrence KM, Sizer BF, Arulampalam TH, Motson RW, Dove E, et al. Locally advanced rectal cancer: Histopathological correlation and predictive accuracy of serial MRI after neoadjuvant chemotherapy. Br J Radiol 2009; 82:332-6.
  • 4 Kerr SF, Norton S, Glynne-Jones R. Delaying surgery after neoadjuvant chemoradiotherapy for rectal cancer may reduce postoperative morbidity without compromising prognosis. Br J Surg 2008;95:1534-40.
  • 5 Maas M, Nelemans PJ, Valentini V, Das P, Rödel C, Kuo LJ, et al. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: A pooled analysis of individual patient data. Lancet Oncol 2010;11:835-44.
  • 6 de Campos-Lobato LF, Geisler DP, da Luz Moreira A, Stocchi L, Dietz D, Kalady MF. Neoadjuvant therapy for rectal cancer: The impact of longer interval between chemoradiation and surgery. J Gastrointest Surg 2011;15:444-50.