CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2014; 35(02): 184-186
DOI: 10.4103/0971-5851.138999
CASE REPORT

Liver metastasis in an adolescent treated for third ventricle germ cell tumor

Rikki Premanand Lionel
Pediatric Hematology-Oncology, Pediatrics I, Division of Child Health, Christian Medical College, Vellore, Tamil Nadu, India
,
Arul R. John
Pediatric Hematology-Oncology, Pediatrics I, Division of Child Health, Christian Medical College, Vellore, Tamil Nadu, India
,
Venkatramani Sitaram
Department of Hepatic Pancreatic and Biliary Surgery, Christian Medical College, Vellore, Tamil Nadu, India
,
Leni G. Mathew
Pediatric Hematology-Oncology, Pediatrics I, Division of Child Health, Christian Medical College, Vellore, Tamil Nadu, India
› Author Affiliations

Abstract

Systemic dissemination of intracranial germ cell tumors (GCTs) occur only in 3% of cases and the common sites are bone, lungs, and lymph nodes. Metastasis to the liver is rare. As far as we could find, only six cases of liver metastasis of intracranial GCTs have been reported so far. We report an adolescent girl who presented with hepatic relapse 2½ years after successful completion of treatment of intracranial GCT. She was treated with chemotherapy and right hepatectomy and is doing well 30 months after treatment for the metastatic disease.



Publication History

Article published online:
19 July 2021

© 2014. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Jain A, Sharma MC, Suri V, Kale SS, Mahapatra AK, Tatke M, et al. Spectrum of pediatric brain tumors in India : a0 multi-institutional study. Neurol India 2011;59:208-11.
  • 2 Jennings MT, Gelman R, Hochberg F. Intracranial germ-cell tumors : n0 atural history and pathogenesis. J Neurosurg 1985;63:155-67.
  • 3 Asanuma M, Aoyama T, Sakai K, Asano K, Uehara T, Hongo K. Hematogenous extraneural metastasis of the germinomatous component of a pineal mixed germ cell tumor. Brain Tumor Pathol 2012;29:245-50.
  • 4 Campbell AN, Chan HS, Becker LE, Daneman A, Park TS, Hoffman HJ. Extracranial metastases in childhood primary intracranial tumors. A report of 21 cases and review of the literature. Cancer 1984;53:974-81.
  • 5 Varan A, Sari N, Akalan N, Söylemezoglu F, Akyüz C, Kutluk T, et al. Extraneural metastasis in intracranial tumors in children : t0 he experience of a single center. J Neurooncol 2006;79:187-90.
  • 6 Galassi E, Tognetti F, Frank F, Gaist G. Extraneural metastases from primary pineal tumors. Review of the literature. Surg Neurol 1984;21:497-504.
  • 7 Shinmura F, Takayasu K, Sakata R, Ariwa R, Takagi S. Autopsy case of extra-neural metastasis of suprasellar pineal germinoma. Gan No Rinsho 1983;29:832-7.
  • 8 Motomochi M, Makita Y, Nabeshima S, Aoyama I, Ichijima K, Yamabe H, et al. A case of intracranial germinoma with multiple remote metastases (author′s transl). No Shinkei Geka 1980;8:563-70.
  • 9 Jennings CD, Powell DE, Walsh JW, Mortara RH. Suprasellar germ cell tumor with extracranial metastases. Neurosurgery 1985;16:9-12.
  • 10 Adachi J, Ono N, Misumi S, Tamura M, Ohye C. Multiple liver metastases of a suprasellar germ cell tumor treated with combined chemotherapy of cisplatin and etoposide. No Shinkei Geka 1991;19:671-5.